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- W2093754688 abstract "The aim of present study was to validate hepatoprotective and antioxidant activities of the bark of Bridelia retusa. The aqueous ethanol extract of B. retusa exhibited highest in vitro hepatoprotective effects as evident from the significantly reduced serum glutamate oxaloacetate transaminase (SGOT) and serum glutamate pyruvate transaminase (SGPT) into the incubation medium of rat hepatocytes with carbon tetrachloride (CCl4), over the other organic extracts (chloroform, ethylacetate, and methanol). CCl4 administered through subcutaneous injection produced a marked elevation in the serum levels of GOT, GPT, lactate dehydrogenase, alkaline phosphatase, bilirubin, thiobarbituric acid reactive substances, and decreased in the levels of reduced glutathione, superoxide dismutase, catalase, glutathione-S-transferase, glutathione reductase, glutathione peroxidase, and total protein content. The biochemical activities were normalized in the pretreatment of rats induced by CCl4 with different doses (250 and 500 mg ..." @default.
- W2093754688 created "2016-06-24" @default.
- W2093754688 creator A5037746435 @default.
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- W2093754688 date "2010-08-01" @default.
- W2093754688 modified "2023-09-27" @default.
- W2093754688 title "Hepatoprotective and antioxidant effects ofBridelia retusaagainst carbon tetrachloride-induced hepatotoxicity" @default.
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- W2093754688 doi "https://doi.org/10.1080/02772240903433740" @default.
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