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• W2093755071 endingPage "1137" @default.
• W2093755071 startingPage "1125" @default.
• W2093755071 abstract "We describe a chemotactic-like response of Escherichia coli strains lacking most of the known chemotaxis machinery but containing high levels of the response regulator CheY. The bacteria accumulated in aspartate-containing capillaries, they formed rings on tryptone-containing semisolid agar, and the probability of counterclockwise flagellar rotation transiently increased in response to stimulation with aspartate (10−10–10−5 M; the response was inverted at > 10−4 M). The temporal response was partial and delayed, as was the response of a control wild-type strain having a high CheY level. α-Methyl-DL-aspartate, a non-metabolizable analogue of aspartate as well as other known attractants of E. Coli, glucose and, to a lesser extent, galactose, maltose and serine caused a similar response. So did low concentrations of acetate and benzoate (which, at higher concentrations, act as repellents for wild-type E. coli ). Other tested repellents such as indole, Ni2+ and Co2+ increased the clockwise bias. These observations raise the possibility that, at least when the conventional signal transduction components are missing, a non-conventional chemotactic signal transduction pathway might be functional in E. coli. Potential molecular mechanisms are discussed." @default.
• W2093755071 created "2016-06-24" @default.
• W2093755071 creator A5063601237 @default.
• W2093755071 creator A5090581136 @default.
• W2093755071 date "1999-02-01" @default.
• W2093755071 modified "2023-10-07" @default.
• W2093755071 title "Chemotactic-like response of Escherichia coli cells lacking the known chemotaxis machinery but containing overexpressed CheY" @default.
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• W2093755071 doi "https://doi.org/10.1046/j.1365-2958.1999.01251.x" @default.
• W2093755071 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10096080" @default.
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