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- W2093809581 abstract "Different histamine H3-receptor antagonists have been tested in displacement studies at human and rat H3 receptors in stably transfected cells. Based on an actual rhodopsin structure, models for receptor antagonist interaction were developed for receptors of both species. Similarities and discrepancies in binding profiles can be explained, but not quantified by hydrophilic interactions with Asp114 and an important lipophilic binding pocket modified by two nearby amino acids." @default.
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- W2093809581 date "2001-04-01" @default.
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- W2093809581 title "Different antagonist binding properties of human and rat histamine H3 receptors" @default.
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- W2093809581 doi "https://doi.org/10.1016/s0960-894x(01)00090-7" @default.
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