Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093820900> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2093820900 endingPage "208" @default.
- W2093820900 startingPage "201" @default.
- W2093820900 abstract "This paper addresses the in situ expression of transforming growth factor-β (TGF-β), platelet-derived growth factor (PDGF), and their receptors in the encapsulation process against a foreign body, using 20 cases of the titanium miniplate as a model of the foreign body, used clinically to fix a fractured mandible. Fibrous tissue formed during the encapsulation process was composed of scar-like and fibrogenic layers, with the former directly facing the foreign body. By immunohistochemistry using pre-fixed frozen sections, only the fibrogenic layer was characterized by expression of type I procollagen (PC-I). Spindle-shaped mesenchymal cells in the fibrogenic layer expressed TGF-β isoforms and receptors, PDGF isoforms, and PDGF β-receptor. In contrast, the scar-like layer had few such cells. In both layers, spindle-shaped cells did not express Ki-67 in their nuclei. Double immunofluorescence microscopy for cell identification revealed that most PC-I-positive fibroblasts expressed both isoforms and receptors of TGF-β and PDGF in the fibrogenic layer, while in contrast, they were expressed by only a small number of CD68-positive macrophages. These results suggest that in the maintenance stage of the human encapsulation process against a foreign body, both TGF-β and PDGF function cooperatively via their receptors in the fibrogenic layer, with such stimuli markedly diminished in the scar-like layer. Copyright © 1998 John Wiley & Sons, Ltd." @default.
- W2093820900 created "2016-06-24" @default.
- W2093820900 creator A5060578424 @default.
- W2093820900 creator A5065823706 @default.
- W2093820900 creator A5074802476 @default.
- W2093820900 creator A5091841550 @default.
- W2093820900 date "1998-10-01" @default.
- W2093820900 modified "2023-10-16" @default.
- W2093820900 title "Procollagen-positive fibroblasts predominantly express fibrogenic growth factors and their receptors in human encapsulation process against foreign body" @default.
- W2093820900 cites W1487203123 @default.
- W2093820900 cites W1510586846 @default.
- W2093820900 cites W1513452394 @default.
- W2093820900 cites W1592658968 @default.
- W2093820900 cites W1964726028 @default.
- W2093820900 cites W1968538228 @default.
- W2093820900 cites W1987770511 @default.
- W2093820900 cites W1992369687 @default.
- W2093820900 cites W2001618077 @default.
- W2093820900 cites W2007835360 @default.
- W2093820900 cites W2029545106 @default.
- W2093820900 cites W2039420264 @default.
- W2093820900 cites W2044918751 @default.
- W2093820900 cites W2060896969 @default.
- W2093820900 cites W2077372004 @default.
- W2093820900 cites W2086596508 @default.
- W2093820900 cites W2091664620 @default.
- W2093820900 cites W2100382451 @default.
- W2093820900 cites W2108104357 @default.
- W2093820900 cites W2123550509 @default.
- W2093820900 cites W2148371225 @default.
- W2093820900 cites W2154636701 @default.
- W2093820900 cites W2158464481 @default.
- W2093820900 cites W2159634847 @default.
- W2093820900 cites W2164094961 @default.
- W2093820900 cites W2164279207 @default.
- W2093820900 cites W4211166816 @default.
- W2093820900 doi "https://doi.org/10.1002/(sici)1096-9896(1998100)186:2<201::aid-path157>3.0.co;2-c" @default.
- W2093820900 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9924437" @default.
- W2093820900 hasPublicationYear "1998" @default.
- W2093820900 type Work @default.
- W2093820900 sameAs 2093820900 @default.
- W2093820900 citedByCount "17" @default.
- W2093820900 countsByYear W20938209002013 @default.
- W2093820900 countsByYear W20938209002017 @default.
- W2093820900 countsByYear W20938209002019 @default.
- W2093820900 countsByYear W20938209002022 @default.
- W2093820900 crossrefType "journal-article" @default.
- W2093820900 hasAuthorship W2093820900A5060578424 @default.
- W2093820900 hasAuthorship W2093820900A5065823706 @default.
- W2093820900 hasAuthorship W2093820900A5074802476 @default.
- W2093820900 hasAuthorship W2093820900A5091841550 @default.
- W2093820900 hasConcept C118131993 @default.
- W2093820900 hasConcept C170493617 @default.
- W2093820900 hasConcept C180361614 @default.
- W2093820900 hasConcept C185592680 @default.
- W2093820900 hasConcept C198826908 @default.
- W2093820900 hasConcept C2775960820 @default.
- W2093820900 hasConcept C2781294074 @default.
- W2093820900 hasConcept C55493867 @default.
- W2093820900 hasConcept C86803240 @default.
- W2093820900 hasConcept C95444343 @default.
- W2093820900 hasConceptScore W2093820900C118131993 @default.
- W2093820900 hasConceptScore W2093820900C170493617 @default.
- W2093820900 hasConceptScore W2093820900C180361614 @default.
- W2093820900 hasConceptScore W2093820900C185592680 @default.
- W2093820900 hasConceptScore W2093820900C198826908 @default.
- W2093820900 hasConceptScore W2093820900C2775960820 @default.
- W2093820900 hasConceptScore W2093820900C2781294074 @default.
- W2093820900 hasConceptScore W2093820900C55493867 @default.
- W2093820900 hasConceptScore W2093820900C86803240 @default.
- W2093820900 hasConceptScore W2093820900C95444343 @default.
- W2093820900 hasIssue "2" @default.
- W2093820900 hasLocation W20938209001 @default.
- W2093820900 hasLocation W20938209002 @default.
- W2093820900 hasOpenAccess W2093820900 @default.
- W2093820900 hasPrimaryLocation W20938209001 @default.
- W2093820900 hasRelatedWork W1971652814 @default.
- W2093820900 hasRelatedWork W1984344088 @default.
- W2093820900 hasRelatedWork W1988539054 @default.
- W2093820900 hasRelatedWork W2000406614 @default.
- W2093820900 hasRelatedWork W2021053322 @default.
- W2093820900 hasRelatedWork W2029464998 @default.
- W2093820900 hasRelatedWork W2039569566 @default.
- W2093820900 hasRelatedWork W2078751457 @default.
- W2093820900 hasRelatedWork W2316286889 @default.
- W2093820900 hasRelatedWork W2377198652 @default.
- W2093820900 hasVolume "186" @default.
- W2093820900 isParatext "false" @default.
- W2093820900 isRetracted "false" @default.
- W2093820900 magId "2093820900" @default.
- W2093820900 workType "article" @default.