FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093839816> ?p ?o ?g. }

• W2093839816 endingPage "14" @default.
• W2093839816 startingPage "8" @default.
• W2093839816 abstract "The growth hormone (GH) responses to GH-releasing hormone (GHRH; 1 μg/kg BW in an i.v. bolus), clonidine (150 μg in a single oral dose) and insulin (0.15 IU/kg BW in an i.v. bolus) induced hypoglycemia were evaluated in 7 normal weight bulimic women with regular menstrual cycles and in 7 age- and weight-matched normal women. In addition, the effect of thyrotropin-releasing hormone (TRH; 200 μg in an i.v. bolus) on serum thyroid-stimulating hormone (TSH) and GH levels was measured in the same subjects. Tests were carried out in random order on the 22nd days of the following menstrual cycles. A control test with the i.v. administration of normal saline instead of drugs was carried out 2 days after the TRH test. Basal GH levels were significantly higher in bulimic women than in normal controls; despite higher GH levels, bulimic women showed normal circulating concentrations of somatomedin-C (Sm-C). Serum GH levels remained unmodified during the control test. In contrast, the administration of GHRH, clonidine or insulin induced significant GH responses in all subjects. Bulimic and normal women showed comparable responses after GHRH, clonidine or hypoglycemia. The hypoglycemic response to insulin was similar in bulimic and control subjects. The administration of TRH was unable to increase the circulating levels of GH in the normal controls, whereas it significantly increased GH concentrations in 5 of 7 bulimic women. Delayed TSH responses to TRH were observed in the bulimic group. These data indicate that normal weight bulimia is not accompanied by abnormalities in the hypothalamic pituitary responsiveness to normally acting GH-releasing stimuli. Taken together with the finding of normal plasma Sm-C levels, these results suggest the integrity of the GHRH-GH-somatomedin axis in bulimia. On the other hand, the anomalous effects of TRH suggest an abnormal sensitivity of the GH and TSH secretory systems to TRH in bulimia." @default.
• W2093839816 created "2016-06-24" @default.
• W2093839816 creator A5000581745 @default.
• W2093839816 creator A5006414712 @default.
• W2093839816 creator A5011002328 @default.
• W2093839816 creator A5027259843 @default.
• W2093839816 creator A5034183685 @default.
• W2093839816 creator A5049518816 @default.
• W2093839816 creator A5051870796 @default.
• W2093839816 creator A5052216044 @default.
• W2093839816 creator A5056238629 @default.
• W2093839816 creator A5080053772 @default.
• W2093839816 date "1990-01-01" @default.
• W2093839816 modified "2023-09-24" @default.
• W2093839816 title "Growth Hormone Responses to Growth Hormone-Releasing Hormone, Clonidine and Insulin-Induced Hypoglycemia in Normal Weight Bulimic Women" @default.
• W2093839816 doi "https://doi.org/10.1159/000118708" @default.
• W2093839816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2126361" @default.
• W2093839816 hasPublicationYear "1990" @default.
• W2093839816 type Work @default.
• W2093839816 sameAs 2093839816 @default.
• W2093839816 citedByCount "6" @default.
• W2093839816 countsByYear W20938398162018 @default.
• W2093839816 crossrefType "journal-article" @default.
• W2093839816 hasAuthorship W2093839816A5000581745 @default.
• W2093839816 hasAuthorship W2093839816A5006414712 @default.
• W2093839816 hasAuthorship W2093839816A5011002328 @default.
• W2093839816 hasAuthorship W2093839816A5027259843 @default.
• W2093839816 hasAuthorship W2093839816A5034183685 @default.
• W2093839816 hasAuthorship W2093839816A5049518816 @default.
• W2093839816 hasAuthorship W2093839816A5051870796 @default.
• W2093839816 hasAuthorship W2093839816A5052216044 @default.
• W2093839816 hasAuthorship W2093839816A5056238629 @default.
• W2093839816 hasAuthorship W2093839816A5080053772 @default.
• W2093839816 hasConcept C126322002 @default.
• W2093839816 hasConcept C134018914 @default.
• W2093839816 hasConcept C2776216936 @default.
• W2093839816 hasConcept C2778024521 @default.
• W2093839816 hasConcept C2778399450 @default.
• W2093839816 hasConcept C2779306644 @default.
• W2093839816 hasConcept C2780668416 @default.
• W2093839816 hasConcept C43376680 @default.
• W2093839816 hasConcept C71315377 @default.
• W2093839816 hasConcept C71924100 @default.
• W2093839816 hasConceptScore W2093839816C126322002 @default.
• W2093839816 hasConceptScore W2093839816C134018914 @default.
• W2093839816 hasConceptScore W2093839816C2776216936 @default.
• W2093839816 hasConceptScore W2093839816C2778024521 @default.
• W2093839816 hasConceptScore W2093839816C2778399450 @default.
• W2093839816 hasConceptScore W2093839816C2779306644 @default.
• W2093839816 hasConceptScore W2093839816C2780668416 @default.
• W2093839816 hasConceptScore W2093839816C43376680 @default.
• W2093839816 hasConceptScore W2093839816C71315377 @default.
• W2093839816 hasConceptScore W2093839816C71924100 @default.
• W2093839816 hasIssue "1" @default.
• W2093839816 hasLocation W20938398161 @default.
• W2093839816 hasLocation W20938398162 @default.
• W2093839816 hasOpenAccess W2093839816 @default.
• W2093839816 hasPrimaryLocation W20938398161 @default.
• W2093839816 hasRelatedWork W1999918803 @default.
• W2093839816 hasRelatedWork W2001349399 @default.
• W2093839816 hasRelatedWork W2018460003 @default.
• W2093839816 hasRelatedWork W2027250979 @default.
• W2093839816 hasRelatedWork W2033209790 @default.
• W2093839816 hasRelatedWork W2045993936 @default.
• W2093839816 hasRelatedWork W2048914685 @default.
• W2093839816 hasRelatedWork W2091233188 @default.
• W2093839816 hasRelatedWork W2106532285 @default.
• W2093839816 hasRelatedWork W2271534741 @default.
• W2093839816 hasVolume "23" @default.
• W2093839816 isParatext "false" @default.
• W2093839816 isRetracted "false" @default.
• W2093839816 magId "2093839816" @default.
• W2093839816 workType "article" @default.