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- W2093889413 abstract "1. The influence of season, photoperiod and ambient temperature on the content of proteins, sialo-glycoproteins and gangliosides and on the composition of gangliosides of three different brain regions (cortex, cerebellum and basalbrain) of the Djungarian dwarf hamster (Phodopus sungorus) had been investigated. Concomittantly changes in body wt and fur colouration were recorded. 2. Dwarf hamsters living under natural photoperiod and ambient temperature conditions (“outside”) showed a distinct annual cycle in body wt (summer: about 45 g; winter: about 25 g) and fur colouration (summer: dark grey; winter: whitish). 3. Among the three brain regions the mean concentration of proteins ranged between 120 and 155 mg protein/g wet wt. The sialo-glycoprotein content varied between 260 and 410 μg NeuAc/g wet wt, and that of gangliosides between 800 and 1650 μg NeuAc/g wet wt. Seasonal fluctuations were not found. 4. The composition of brain gangliosides remained uninfluenced throughout the year in the cerebellum, whereas seasonal variations were observed in cortex and basalbrain. 5. Consequently the concentration ratio of the two major mammalian ganglioside fractions GD1a vs GT1b remained almost stable in cerebellum (0.3). In contrast to this the seasonal values of cortex and basalbrain changed from 0.6 and 0.8 in winter to 0.7 and 1.1 in summer. This indicated a higher polarity of the gangliosides in these brain regions during cold adaptation. 6. The results are discussed with regard to modulatory functions of neuronal gangliosides for the process of synaptic transmission during seasonal adaptation." @default.
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- W2093889413 date "1987-01-01" @default.
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- W2093889413 title "Seasonal variability of sialo-glycoconjugates in the brain of the Djungarian hamster (Phodopus sungorus)" @default.
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- W2093889413 doi "https://doi.org/10.1016/0305-0491(87)90309-9" @default.
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