Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093897902> ?p ?o ?g. }
- W2093897902 endingPage "202" @default.
- W2093897902 startingPage "188" @default.
- W2093897902 abstract "Nine commonly studied Simian virus 40 (SV40)-transformed rodent cell lines were screened for tumor (T) antigens defective in SV40 DNA replication using a simple polyethylene glycol-mediated cell fusion assay. Each line contained a functional origin of SV40 DNA replication, as shown by fusion with Cos 1 cells. Fusion with uninfected monkey cells revealed that T antigens from two lines lacked detectable replicative activity, while T antigens from five other lines exhibited only very weak replicative activity. One line, and a tumor cell line derived from it, expressed T antigen with wild-type replication activity. Biochemical analysis of these proteins revealed defects in DNA binding activity and ATPase activity. One line expressed large T antigen defective in both activities. All of the lines contained complexes of T antigen with the cellular protein p53 and all of the T antigens exhibited nucleotide-binding activity. The results indicate that some of these lines may constitute a useful source of new replication-defective T antigens." @default.
- W2093897902 created "2016-06-24" @default.
- W2093897902 creator A5019347097 @default.
- W2093897902 creator A5032492719 @default.
- W2093897902 creator A5046478195 @default.
- W2093897902 creator A5079841042 @default.
- W2093897902 date "1985-10-01" @default.
- W2093897902 modified "2023-09-28" @default.
- W2093897902 title "Identification and biochemical analysis of DNA replication-defective large T antigens from SV40-transformed cells" @default.
- W2093897902 cites W1480080334 @default.
- W2093897902 cites W1482051809 @default.
- W2093897902 cites W1484799046 @default.
- W2093897902 cites W1494195428 @default.
- W2093897902 cites W1501360839 @default.
- W2093897902 cites W1502663555 @default.
- W2093897902 cites W1511501520 @default.
- W2093897902 cites W1541280749 @default.
- W2093897902 cites W1546632589 @default.
- W2093897902 cites W1568744107 @default.
- W2093897902 cites W1573289384 @default.
- W2093897902 cites W1574025064 @default.
- W2093897902 cites W1575830633 @default.
- W2093897902 cites W1598680760 @default.
- W2093897902 cites W1858391321 @default.
- W2093897902 cites W1874646775 @default.
- W2093897902 cites W1875257387 @default.
- W2093897902 cites W1892395328 @default.
- W2093897902 cites W1892859196 @default.
- W2093897902 cites W1951756637 @default.
- W2093897902 cites W1963949170 @default.
- W2093897902 cites W1965212866 @default.
- W2093897902 cites W1967446284 @default.
- W2093897902 cites W1968010633 @default.
- W2093897902 cites W1977461031 @default.
- W2093897902 cites W1985203032 @default.
- W2093897902 cites W1996055400 @default.
- W2093897902 cites W1997987172 @default.
- W2093897902 cites W1999002923 @default.
- W2093897902 cites W2014761464 @default.
- W2093897902 cites W2015719364 @default.
- W2093897902 cites W2016505381 @default.
- W2093897902 cites W2033013773 @default.
- W2093897902 cites W2048518879 @default.
- W2093897902 cites W2049076737 @default.
- W2093897902 cites W2063450941 @default.
- W2093897902 cites W2064204579 @default.
- W2093897902 cites W2067419418 @default.
- W2093897902 cites W2068073829 @default.
- W2093897902 cites W2081330030 @default.
- W2093897902 cites W2088150538 @default.
- W2093897902 cites W2088167128 @default.
- W2093897902 cites W2091972651 @default.
- W2093897902 cites W2106319169 @default.
- W2093897902 cites W2125026993 @default.
- W2093897902 cites W2128055739 @default.
- W2093897902 cites W2143863925 @default.
- W2093897902 cites W2154685160 @default.
- W2093897902 cites W2166270104 @default.
- W2093897902 cites W2167375705 @default.
- W2093897902 cites W2167489116 @default.
- W2093897902 cites W2170398046 @default.
- W2093897902 cites W2175671364 @default.
- W2093897902 cites W271573927 @default.
- W2093897902 cites W4230691452 @default.
- W2093897902 cites W4253280851 @default.
- W2093897902 doi "https://doi.org/10.1016/0042-6822(85)90003-0" @default.
- W2093897902 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2996217" @default.
- W2093897902 hasPublicationYear "1985" @default.
- W2093897902 type Work @default.
- W2093897902 sameAs 2093897902 @default.
- W2093897902 citedByCount "20" @default.
- W2093897902 crossrefType "journal-article" @default.
- W2093897902 hasAuthorship W2093897902A5019347097 @default.
- W2093897902 hasAuthorship W2093897902A5032492719 @default.
- W2093897902 hasAuthorship W2093897902A5046478195 @default.
- W2093897902 hasAuthorship W2093897902A5079841042 @default.
- W2093897902 hasConcept C140704245 @default.
- W2093897902 hasConcept C147483822 @default.
- W2093897902 hasConcept C153911025 @default.
- W2093897902 hasConcept C159047783 @default.
- W2093897902 hasConcept C188036394 @default.
- W2093897902 hasConcept C2522874641 @default.
- W2093897902 hasConcept C54355233 @default.
- W2093897902 hasConcept C552990157 @default.
- W2093897902 hasConcept C58337764 @default.
- W2093897902 hasConcept C73573662 @default.
- W2093897902 hasConcept C81885089 @default.
- W2093897902 hasConcept C86803240 @default.
- W2093897902 hasConcept C98086919 @default.
- W2093897902 hasConceptScore W2093897902C140704245 @default.
- W2093897902 hasConceptScore W2093897902C147483822 @default.
- W2093897902 hasConceptScore W2093897902C153911025 @default.
- W2093897902 hasConceptScore W2093897902C159047783 @default.
- W2093897902 hasConceptScore W2093897902C188036394 @default.
- W2093897902 hasConceptScore W2093897902C2522874641 @default.
- W2093897902 hasConceptScore W2093897902C54355233 @default.
- W2093897902 hasConceptScore W2093897902C552990157 @default.
- W2093897902 hasConceptScore W2093897902C58337764 @default.