FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2093938183> ?p ?o ?g. }

• W2093938183 endingPage "13" @default.
• W2093938183 startingPage "6" @default.
• W2093938183 abstract "Myocardial infarcts in mammals heal by scar formation rather than formation of new muscle tissue. The MRL/MpJ [Murphy Roths large (MRL) derived by the Murphy group of the Jackson Laboratory (MpJ)] mouse, however, has been reported to exhibit minimal scarring and subsequent cardiac regeneration after cryoinjury of the right ventricle. Other groups have reported that permanent and temporary ligation of the coronary artery resulted in scarring without regeneration.To clarify these contradictory results, we studied the temporal evolution of infarcts in MRL/MpJ and C57BL/6 control mice from 1 to 90 days post injury and the effects of intrathoracic cryoinjury to 28 days.After infarction, the conversion from necrotic myocardium to granulation tissue and then to scar proceeded identically in the two groups. Infarct DNA synthesis, measured by incorporation of a 5-bromo-2-deoxyuridine pulse, peaked at 4 days in both strains and did not differ between strains at any time point. Endothelial cell and total vascular density in the both the infarcted and noninfarcted cardiac tissue did not differ between groups at any time. Histological analysis of directly cryoinjured right and left ventricular myocardium showed indistinguishable wound healing in both strains, and final scar size was identical in each group.These studies demonstrate that both myocardial infarcts and cryoinjuries in MRL/MpJ mice heal by typical scar formation rather than muscle regeneration, in a manner very similar to C57BL/6 controls. We conclude that the MRL mouse is not a model for myocardial regeneration." @default.
• W2093938183 created "2016-06-24" @default.
• W2093938183 creator A5077140689 @default.
• W2093938183 creator A5083709070 @default.
• W2093938183 date "2008-01-01" @default.
• W2093938183 modified "2023-10-03" @default.
• W2093938183 title "Absence of regeneration in the MRL/MpJ mouse heart following infarction or cryoinjury" @default.
• W2093938183 cites W114991944 @default.
• W2093938183 cites W1965352549 @default.
• W2093938183 cites W1968099944 @default.
• W2093938183 cites W1989238977 @default.
• W2093938183 cites W1993804921 @default.
• W2093938183 cites W1994128832 @default.
• W2093938183 cites W1999131060 @default.
• W2093938183 cites W2004728533 @default.
• W2093938183 cites W2010886666 @default.
• W2093938183 cites W2011267098 @default.
• W2093938183 cites W2034340924 @default.
• W2093938183 cites W2060872964 @default.
• W2093938183 cites W2073420780 @default.
• W2093938183 cites W2084109090 @default.
• W2093938183 cites W2084699825 @default.
• W2093938183 cites W2086933996 @default.
• W2093938183 cites W2087604634 @default.
• W2093938183 cites W2092377409 @default.
• W2093938183 cites W2096913886 @default.
• W2093938183 cites W2099647647 @default.
• W2093938183 cites W2110667326 @default.
• W2093938183 cites W2125635123 @default.
• W2093938183 cites W2126747203 @default.
• W2093938183 cites W2127802096 @default.
• W2093938183 cites W2133117273 @default.
• W2093938183 cites W2137625635 @default.
• W2093938183 cites W2151722542 @default.
• W2093938183 cites W2409367523 @default.
• W2093938183 cites W4242965605 @default.
• W2093938183 doi "https://doi.org/10.1016/j.carpath.2007.01.005" @default.
• W2093938183 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2766607" @default.
• W2093938183 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18160055" @default.
• W2093938183 hasPublicationYear "2008" @default.
• W2093938183 type Work @default.
• W2093938183 sameAs 2093938183 @default.
• W2093938183 citedByCount "41" @default.
• W2093938183 countsByYear W20939381832012 @default.
• W2093938183 countsByYear W20939381832013 @default.
• W2093938183 countsByYear W20939381832014 @default.
• W2093938183 countsByYear W20939381832015 @default.
• W2093938183 countsByYear W20939381832016 @default.
• W2093938183 countsByYear W20939381832017 @default.
• W2093938183 countsByYear W20939381832018 @default.
• W2093938183 countsByYear W20939381832019 @default.
• W2093938183 countsByYear W20939381832020 @default.
• W2093938183 countsByYear W20939381832021 @default.
• W2093938183 countsByYear W20939381832022 @default.
• W2093938183 countsByYear W20939381832023 @default.
• W2093938183 crossrefType "journal-article" @default.
• W2093938183 hasAuthorship W2093938183A5077140689 @default.
• W2093938183 hasAuthorship W2093938183A5083709070 @default.
• W2093938183 hasBestOaLocation W20939381832 @default.
• W2093938183 hasConcept C105702510 @default.
• W2093938183 hasConcept C126322002 @default.
• W2093938183 hasConcept C141071460 @default.
• W2093938183 hasConcept C142724271 @default.
• W2093938183 hasConcept C164705383 @default.
• W2093938183 hasConcept C171056886 @default.
• W2093938183 hasConcept C179437574 @default.
• W2093938183 hasConcept C207200792 @default.
• W2093938183 hasConcept C2776055305 @default.
• W2093938183 hasConcept C2777798775 @default.
• W2093938183 hasConcept C2778921608 @default.
• W2093938183 hasConcept C2780269544 @default.
• W2093938183 hasConcept C3018954641 @default.
• W2093938183 hasConcept C500558357 @default.
• W2093938183 hasConcept C71924100 @default.
• W2093938183 hasConcept C86803240 @default.
• W2093938183 hasConcept C95444343 @default.
• W2093938183 hasConceptScore W2093938183C105702510 @default.
• W2093938183 hasConceptScore W2093938183C126322002 @default.
• W2093938183 hasConceptScore W2093938183C141071460 @default.
• W2093938183 hasConceptScore W2093938183C142724271 @default.
• W2093938183 hasConceptScore W2093938183C164705383 @default.
• W2093938183 hasConceptScore W2093938183C171056886 @default.
• W2093938183 hasConceptScore W2093938183C179437574 @default.
• W2093938183 hasConceptScore W2093938183C207200792 @default.
• W2093938183 hasConceptScore W2093938183C2776055305 @default.
• W2093938183 hasConceptScore W2093938183C2777798775 @default.
• W2093938183 hasConceptScore W2093938183C2778921608 @default.
• W2093938183 hasConceptScore W2093938183C2780269544 @default.
• W2093938183 hasConceptScore W2093938183C3018954641 @default.
• W2093938183 hasConceptScore W2093938183C500558357 @default.
• W2093938183 hasConceptScore W2093938183C71924100 @default.
• W2093938183 hasConceptScore W2093938183C86803240 @default.
• W2093938183 hasConceptScore W2093938183C95444343 @default.
• W2093938183 hasIssue "1" @default.
• W2093938183 hasLocation W20939381831 @default.
• W2093938183 hasLocation W20939381832 @default.
• W2093938183 hasLocation W20939381833 @default.
• W2093938183 hasLocation W20939381834 @default.

• next