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- W2093940226 abstract "An analogue of gonadotropin-releasing hormone, [D-Ala6, des Gly10] mammalian GnRH ethylamide (mGnRH-A) was effective in advancing maturation of Pacific herring (Clupea harengus pallasi) provided the fish had matured to Hay's modified Hjort stage IV (gonads are two-thirds of mature size; germinal vesicles have not migrated). The analogue was administered in new ‘quick-release’ cholesterol pellets made of cholesterol and cellulose (4:1, ww). In vitro perfusion studies indicated 94% of the 100 μg of mGnRH was released from such pellets during 12 h. Implanted ‘quick-release’ mGnRH-A pellets resulted in more mature fish; the advancement over control fish was maintained for at least 3 weeks. Also, a higher percentage of fish reached a more mature Hjort's stage in response to mGnRH in pellets containing 100 μg (dose approximately 800–1000 μg/kg) compared with 20 μg (dose approximately 170–220 μg/kg). The response to different GnRH analogues may be species specific because [D-Ala6, des Gly10] salmon GnRH ethylamide was not effective in herring, but is known to be as effective as mGnRH-A in milkfish. A potential application of mGnRH-A is to advance maturation of stage IV herring kept in captivity (impounded) for commercial production of spawn-on-kelp." @default.
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- W2093940226 date "1988-05-01" @default.
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- W2093940226 title "Induced sexual maturation of herring using GnRH ‘quick-release’ cholesterol pellets" @default.
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- W2093940226 doi "https://doi.org/10.1016/0044-8486(88)90015-4" @default.
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