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- W2094004825 abstract "Activity levels of calcium/phospholipid-dependent protein kinase were examined in preparations of atria and ventricles from embryonic chick hearts at various stages of development. Activity of protein kinase C was much higher in atria than ventricles. Protein kinase C activity underwent a progressive increase in atria during cardiogenesis, being highest just prior to hatching, followed by a profound decrease in activity after hatching. In constrast, activity of cyclic AMP-dependent protein kinase (protein kinase A), while also higher in atria than ventricles, remained relatively constant at the developmental stages examined, likewise decreasing following hatching. These progressive changes in atrial protein kinase C activity suggest a potential regulatory role for this enzyme in cardiogenesis." @default.
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- W2094004825 date "1988-10-01" @default.
- W2094004825 modified "2023-09-27" @default.
- W2094004825 title "Protein kinase C (calcium/phospholipid-dependent protein kinase) in developing chick heart: selective localization to atrium versus ventricle and changes in a" @default.
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- W2094004825 doi "https://doi.org/10.1016/s0005-2728(88)80097-5" @default.
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