Matches in SemOpenAlex for { <https://semopenalex.org/work/W2094014796> ?p ?o ?g. }
- W2094014796 endingPage "180" @default.
- W2094014796 startingPage "173" @default.
- W2094014796 abstract "Vascular responses of the isolated and perfused canine coronary artery to adenosine 5′-triphosphate (ATP) were analyzed pharmacologically. At basal perfusion pressure, ATP induced a vasoconstriction followed by a vasodilation dose-dependently. The potency order for vasoconstriction was α,β-methylene ATP>2-methylthio ATP>UTP>ATP. That for vasodilation was ATP>2-methylthio ATP>α,β-methylene ATP≫UTP in the preparations precontracted by 20 mM KCl. Aminophylline inhibited the vasodilation induced by adenosine, but not that induced by ATP. α,β-Methylene ATP and suramin inhibited the vasoconstriction induced by ATP. Reactive blue 2 inhibited the vasodilation induced by ATP, but not the vasoconstriction. Removal of the endothelium by saponin and l-NG-nitroarginine inhibited the vasodilation induced by ATP, but indomethacin did not. The results suggest that ATP induces vasoconstriction via P2X purinoceptors on the smooth muscle and vasodilation via P2Y purinoceptors on the endothelium through mainly the release of nitric oxide in the canine coronary artery, respectively." @default.
- W2094014796 created "2016-06-24" @default.
- W2094014796 creator A5016706916 @default.
- W2094014796 creator A5042316580 @default.
- W2094014796 creator A5068615681 @default.
- W2094014796 date "1997-09-01" @default.
- W2094014796 modified "2023-10-15" @default.
- W2094014796 title "Pharmacological analysis of responses to ATP in the isolated and perfused canine coronary artery" @default.
- W2094014796 cites W1543593316 @default.
- W2094014796 cites W1815757713 @default.
- W2094014796 cites W1947888345 @default.
- W2094014796 cites W1969833737 @default.
- W2094014796 cites W1970544809 @default.
- W2094014796 cites W1970927892 @default.
- W2094014796 cites W1973602718 @default.
- W2094014796 cites W1979152924 @default.
- W2094014796 cites W1981314671 @default.
- W2094014796 cites W1981461802 @default.
- W2094014796 cites W1982136199 @default.
- W2094014796 cites W1982821411 @default.
- W2094014796 cites W1986552791 @default.
- W2094014796 cites W2000989410 @default.
- W2094014796 cites W2001789263 @default.
- W2094014796 cites W2002019101 @default.
- W2094014796 cites W2009458859 @default.
- W2094014796 cites W2021184142 @default.
- W2094014796 cites W2023204231 @default.
- W2094014796 cites W2026398072 @default.
- W2094014796 cites W2034441038 @default.
- W2094014796 cites W2035574759 @default.
- W2094014796 cites W2038602542 @default.
- W2094014796 cites W2053754499 @default.
- W2094014796 cites W2057947793 @default.
- W2094014796 cites W2061968837 @default.
- W2094014796 cites W2065009203 @default.
- W2094014796 cites W2073946901 @default.
- W2094014796 cites W2078323484 @default.
- W2094014796 cites W2082978448 @default.
- W2094014796 cites W2104234386 @default.
- W2094014796 cites W2129367506 @default.
- W2094014796 doi "https://doi.org/10.1016/s0014-2999(97)01167-9" @default.
- W2094014796 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9369346" @default.
- W2094014796 hasPublicationYear "1997" @default.
- W2094014796 type Work @default.
- W2094014796 sameAs 2094014796 @default.
- W2094014796 citedByCount "20" @default.
- W2094014796 countsByYear W20940147962012 @default.
- W2094014796 countsByYear W20940147962013 @default.
- W2094014796 countsByYear W20940147962018 @default.
- W2094014796 countsByYear W20940147962019 @default.
- W2094014796 countsByYear W20940147962023 @default.
- W2094014796 crossrefType "journal-article" @default.
- W2094014796 hasAuthorship W2094014796A5016706916 @default.
- W2094014796 hasAuthorship W2094014796A5042316580 @default.
- W2094014796 hasAuthorship W2094014796A5068615681 @default.
- W2094014796 hasConcept C120770815 @default.
- W2094014796 hasConcept C126322002 @default.
- W2094014796 hasConcept C134018914 @default.
- W2094014796 hasConcept C170493617 @default.
- W2094014796 hasConcept C185592680 @default.
- W2094014796 hasConcept C2776182878 @default.
- W2094014796 hasConcept C2776991684 @default.
- W2094014796 hasConcept C2779395532 @default.
- W2094014796 hasConcept C2779564974 @default.
- W2094014796 hasConcept C2779961880 @default.
- W2094014796 hasConcept C2909076160 @default.
- W2094014796 hasConcept C2992686903 @default.
- W2094014796 hasConcept C519581460 @default.
- W2094014796 hasConcept C57306754 @default.
- W2094014796 hasConcept C71924100 @default.
- W2094014796 hasConcept C98274493 @default.
- W2094014796 hasConceptScore W2094014796C120770815 @default.
- W2094014796 hasConceptScore W2094014796C126322002 @default.
- W2094014796 hasConceptScore W2094014796C134018914 @default.
- W2094014796 hasConceptScore W2094014796C170493617 @default.
- W2094014796 hasConceptScore W2094014796C185592680 @default.
- W2094014796 hasConceptScore W2094014796C2776182878 @default.
- W2094014796 hasConceptScore W2094014796C2776991684 @default.
- W2094014796 hasConceptScore W2094014796C2779395532 @default.
- W2094014796 hasConceptScore W2094014796C2779564974 @default.
- W2094014796 hasConceptScore W2094014796C2779961880 @default.
- W2094014796 hasConceptScore W2094014796C2909076160 @default.
- W2094014796 hasConceptScore W2094014796C2992686903 @default.
- W2094014796 hasConceptScore W2094014796C519581460 @default.
- W2094014796 hasConceptScore W2094014796C57306754 @default.
- W2094014796 hasConceptScore W2094014796C71924100 @default.
- W2094014796 hasConceptScore W2094014796C98274493 @default.
- W2094014796 hasIssue "2-3" @default.
- W2094014796 hasLocation W20940147961 @default.
- W2094014796 hasLocation W20940147962 @default.
- W2094014796 hasOpenAccess W2094014796 @default.
- W2094014796 hasPrimaryLocation W20940147961 @default.
- W2094014796 hasRelatedWork W1557228442 @default.
- W2094014796 hasRelatedWork W1973856990 @default.
- W2094014796 hasRelatedWork W2000937353 @default.
- W2094014796 hasRelatedWork W2029432559 @default.
- W2094014796 hasRelatedWork W2056373979 @default.
- W2094014796 hasRelatedWork W2070342604 @default.