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- W2094087911 abstract "To determine the effect of passive cigarette smoke on birthweight in pregnant women with asthma as compared to similar women with no cigarette smoke exposure. Prospective observational cohort study, from December 1994 through March 1999, of pregnant women with mild and moderate-severe asthma. A questionnaire was given to each patient detailing smoking history and passive household smoke exposure. Pregnancy outcomes were collected and analyzed with respect to tobacco smoke exposure. Kruskal-Wallis statistic and analysis of covariance were used to test for significance. 1812 women were enrolled during the study period and 342 (19%) smoked cigarettes. Mean birthweights by smoking exposure are listed below and differ significantly (P<0.0001) using women without smoke exposure as the reference standard. These findings did not differ when adjusted for insurance status, education, oral corticosteroid use, EGA, illicit substance use, or asthma severity. Race was a significant factor and was controlled for in the subsequent analyses. In the women who did not smoke, passive smoke was associated with decreased birth weight (P = 0.02). Pairwise comparison of the two maternal smoking to the two nonsmoking subcategories shows significant decrease in infant birthweights (P<0.01 in all cases). In women who smoked, there was no additional decrease in birthweight if there was also household smoke exposure (P = 0.88). Passive cigarette smoke leads to decreased birthweight in asthmatic pregnant women who do not smoke. There is no decrease in birthweight among smokers with additional household smoke exposure. Tabled 1Study PatientHousehold Smoke ExposureNMean Birthweight (gms)Non-smokerNo8273208±673Non-smokerYes6433109±672SmokerNo1012981±753SmokerYes2412996±685 Open table in a new tab" @default.
- W2094087911 created "2016-06-24" @default.
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- W2094087911 date "2003-12-01" @default.
- W2094087911 modified "2023-09-24" @default.
- W2094087911 title "The effect of passive cigarette smoke on birthweight in pregnant women with asthma" @default.
- W2094087911 doi "https://doi.org/10.1016/j.ajog.2003.10.305" @default.
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