FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2094104507> ?p ?o ?g. }

• W2094104507 endingPage "102" @default.
• W2094104507 startingPage "99" @default.
• W2094104507 abstract "A transient abnormal myelopoiesis was observed in a newborn with Down syndrome. Cytogenetic study revealed multiple oligoclonal abnormalities: 47,XY,inv(6)(p23q21),+21c[3]/47,XY,der(7)t(1;7)(q25;p15),+21c[1]/47,XY,del(13)(q?),+21c[1]/47,XY,+21c[15]. Ten months after the patient achieved remission, the transient abnormal myelopoiesis evolved to an acute megakaryoblastic leukemia. Cytogenetic study revealed only a single clonal abnormality, 47,XY,der(7)t(1;7)(q25;p15),+21c, identical to one of the structural changes seen at birth. Sequence analysis of the GATA1 gene revealed a deletion-insertion mutation within the exon 2 introducing a stop codon after Arg 64. It may be that the der(7)t(1;7)(q25;p15) abnormality played some selective role in the development of acute megakaryoblastic leukemia in this patient. To our knowledge, the present case is unique in demonstrating a subclone with der(7)t(1;7)(q25;p15) evolving to acute leukemia." @default.
• W2094104507 created "2016-06-24" @default.
• W2094104507 creator A5019132078 @default.
• W2094104507 creator A5023951654 @default.
• W2094104507 creator A5031826187 @default.
• W2094104507 creator A5059352291 @default.
• W2094104507 creator A5071027835 @default.
• W2094104507 creator A5087756926 @default.
• W2094104507 date "2009-01-01" @default.
• W2094104507 modified "2023-09-23" @default.
• W2094104507 title "Transient abnormal myelopoiesis in a Down syndrome newborn followed by acute myeloid leukemia: identification of the same chromosomal abnormality in both stages" @default.
• W2094104507 cites W103664678 @default.
• W2094104507 cites W161546139 @default.
• W2094104507 cites W1757434972 @default.
• W2094104507 cites W1973787218 @default.
• W2094104507 cites W1976386009 @default.
• W2094104507 cites W2004290874 @default.
• W2094104507 cites W2007565222 @default.
• W2094104507 cites W2020177242 @default.
• W2094104507 cites W2044678489 @default.
• W2094104507 cites W2064374727 @default.
• W2094104507 cites W2073527879 @default.
• W2094104507 cites W2075455790 @default.
• W2094104507 cites W2075626785 @default.
• W2094104507 cites W2085362362 @default.
• W2094104507 cites W2089444911 @default.
• W2094104507 cites W2090956216 @default.
• W2094104507 cites W2129652709 @default.
• W2094104507 cites W2130476801 @default.
• W2094104507 cites W2132473369 @default.
• W2094104507 cites W2143615866 @default.
• W2094104507 cites W2221252373 @default.
• W2094104507 cites W43873339 @default.
• W2094104507 doi "https://doi.org/10.1016/j.cancergencyto.2008.08.011" @default.
• W2094104507 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19100513" @default.
• W2094104507 hasPublicationYear "2009" @default.
• W2094104507 type Work @default.
• W2094104507 sameAs 2094104507 @default.
• W2094104507 citedByCount "2" @default.
• W2094104507 countsByYear W20941045072017 @default.
• W2094104507 crossrefType "journal-article" @default.
• W2094104507 hasAuthorship W2094104507A5019132078 @default.
• W2094104507 hasAuthorship W2094104507A5023951654 @default.
• W2094104507 hasAuthorship W2094104507A5031826187 @default.
• W2094104507 hasAuthorship W2094104507A5059352291 @default.
• W2094104507 hasAuthorship W2094104507A5071027835 @default.
• W2094104507 hasAuthorship W2094104507A5087756926 @default.
• W2094104507 hasConcept C104317684 @default.
• W2094104507 hasConcept C109159458 @default.
• W2094104507 hasConcept C118552586 @default.
• W2094104507 hasConcept C150194340 @default.
• W2094104507 hasConcept C192196715 @default.
• W2094104507 hasConcept C203014093 @default.
• W2094104507 hasConcept C2778378607 @default.
• W2094104507 hasConcept C2778461978 @default.
• W2094104507 hasConcept C2778729363 @default.
• W2094104507 hasConcept C2779282312 @default.
• W2094104507 hasConcept C2779954681 @default.
• W2094104507 hasConcept C2780189214 @default.
• W2094104507 hasConcept C28328180 @default.
• W2094104507 hasConcept C2908755955 @default.
• W2094104507 hasConcept C30481170 @default.
• W2094104507 hasConcept C36823959 @default.
• W2094104507 hasConcept C501734568 @default.
• W2094104507 hasConcept C50965678 @default.
• W2094104507 hasConcept C53226629 @default.
• W2094104507 hasConcept C54355233 @default.
• W2094104507 hasConcept C71924100 @default.
• W2094104507 hasConcept C86803240 @default.
• W2094104507 hasConcept C95862172 @default.
• W2094104507 hasConceptScore W2094104507C104317684 @default.
• W2094104507 hasConceptScore W2094104507C109159458 @default.
• W2094104507 hasConceptScore W2094104507C118552586 @default.
• W2094104507 hasConceptScore W2094104507C150194340 @default.
• W2094104507 hasConceptScore W2094104507C192196715 @default.
• W2094104507 hasConceptScore W2094104507C203014093 @default.
• W2094104507 hasConceptScore W2094104507C2778378607 @default.
• W2094104507 hasConceptScore W2094104507C2778461978 @default.
• W2094104507 hasConceptScore W2094104507C2778729363 @default.
• W2094104507 hasConceptScore W2094104507C2779282312 @default.
• W2094104507 hasConceptScore W2094104507C2779954681 @default.
• W2094104507 hasConceptScore W2094104507C2780189214 @default.
• W2094104507 hasConceptScore W2094104507C28328180 @default.
• W2094104507 hasConceptScore W2094104507C2908755955 @default.
• W2094104507 hasConceptScore W2094104507C30481170 @default.
• W2094104507 hasConceptScore W2094104507C36823959 @default.
• W2094104507 hasConceptScore W2094104507C501734568 @default.
• W2094104507 hasConceptScore W2094104507C50965678 @default.
• W2094104507 hasConceptScore W2094104507C53226629 @default.
• W2094104507 hasConceptScore W2094104507C54355233 @default.
• W2094104507 hasConceptScore W2094104507C71924100 @default.
• W2094104507 hasConceptScore W2094104507C86803240 @default.
• W2094104507 hasConceptScore W2094104507C95862172 @default.
• W2094104507 hasIssue "2" @default.
• W2094104507 hasLocation W20941045071 @default.
• W2094104507 hasLocation W20941045072 @default.
• W2094104507 hasOpenAccess W2094104507 @default.
• W2094104507 hasPrimaryLocation W20941045071 @default.

• next