FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2094115819> ?p ?o ?g. }

• W2094115819 endingPage "e40816" @default.
• W2094115819 startingPage "e40816" @default.
• W2094115819 abstract "Histone deacetylase (HDAC) inhibitors, especially vorinostat, are currently under investigation as potential adjuncts in the treatment of neuroblastoma. The effect of vorinostat co-treatment on the development of resistance to other chemotherapeutic agents is unknown. In the present study, we treated two human neuroblastoma cell lines [SK-N-SH and SK-N-Be(2)C] with progressively increasing doses of doxorubicin under two conditions: with and without vorinsotat co-therapy. The resultant doxorubicin-resistant (DoxR) and vorinostat-treated doxorubicin resistant (DoxR-v) cells were equally resistant to doxorubicin despite significantly lower P-glycoprotein expression in the DoxR-v cells. Whole genome analysis was performed using the Ilumina Human HT-12 v4 Expression Beadchip to identify genes with differential expression unique to the DoxR-v cells. We uncovered a number of genes whose differential expression in the DoxR-v cells might contribute to their resistant phenotype, including hypoxia inducible factor-2. Finally, we used Gene Ontology to categorize the biological functions of the differentially expressed genes unique to the DoxR-v cells and found that genes involved in cellular metabolism were especially affected." @default.
• W2094115819 created "2016-06-24" @default.
• W2094115819 creator A5006375381 @default.
• W2094115819 creator A5010860843 @default.
• W2094115819 creator A5012007158 @default.
• W2094115819 creator A5013618564 @default.
• W2094115819 creator A5016181204 @default.
• W2094115819 creator A5049966575 @default.
• W2094115819 creator A5068782130 @default.
• W2094115819 creator A5069829773 @default.
• W2094115819 creator A5072042288 @default.
• W2094115819 date "2012-07-19" @default.
• W2094115819 modified "2023-09-30" @default.
• W2094115819 title "The Effect of Vorinostat on the Development of Resistance to Doxorubicin in Neuroblastoma" @default.
• W2094115819 cites W1978835020 @default.
• W2094115819 cites W1990607537 @default.
• W2094115819 cites W1995364339 @default.
• W2094115819 cites W1999513100 @default.
• W2094115819 cites W2000533287 @default.
• W2094115819 cites W2010837115 @default.
• W2094115819 cites W2012134224 @default.
• W2094115819 cites W2018272903 @default.
• W2094115819 cites W2020681708 @default.
• W2094115819 cites W2052777173 @default.
• W2094115819 cites W2081098333 @default.
• W2094115819 cites W2101546733 @default.
• W2094115819 cites W2106608030 @default.
• W2094115819 cites W2108573150 @default.
• W2094115819 cites W2117083685 @default.
• W2094115819 cites W2117596702 @default.
• W2094115819 cites W2120084347 @default.
• W2094115819 cites W2120865735 @default.
• W2094115819 cites W2132154679 @default.
• W2094115819 cites W2135103035 @default.
• W2094115819 cites W2144999788 @default.
• W2094115819 cites W2147800896 @default.
• W2094115819 cites W2148396794 @default.
• W2094115819 cites W2169824207 @default.
• W2094115819 cites W2171387445 @default.
• W2094115819 cites W53566393 @default.
• W2094115819 doi "https://doi.org/10.1371/journal.pone.0040816" @default.
• W2094115819 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3400660" @default.
• W2094115819 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22829886" @default.
• W2094115819 hasPublicationYear "2012" @default.
• W2094115819 type Work @default.
• W2094115819 sameAs 2094115819 @default.
• W2094115819 citedByCount "13" @default.
• W2094115819 countsByYear W20941158192013 @default.
• W2094115819 countsByYear W20941158192015 @default.
• W2094115819 countsByYear W20941158192016 @default.
• W2094115819 countsByYear W20941158192020 @default.
• W2094115819 countsByYear W20941158192021 @default.
• W2094115819 countsByYear W20941158192022 @default.
• W2094115819 countsByYear W20941158192023 @default.
• W2094115819 crossrefType "journal-article" @default.
• W2094115819 hasAuthorship W2094115819A5006375381 @default.
• W2094115819 hasAuthorship W2094115819A5010860843 @default.
• W2094115819 hasAuthorship W2094115819A5012007158 @default.
• W2094115819 hasAuthorship W2094115819A5013618564 @default.
• W2094115819 hasAuthorship W2094115819A5016181204 @default.
• W2094115819 hasAuthorship W2094115819A5049966575 @default.
• W2094115819 hasAuthorship W2094115819A5068782130 @default.
• W2094115819 hasAuthorship W2094115819A5069829773 @default.
• W2094115819 hasAuthorship W2094115819A5072042288 @default.
• W2094115819 hasBestOaLocation W20941158191 @default.
• W2094115819 hasConcept C104317684 @default.
• W2094115819 hasConcept C127716648 @default.
• W2094115819 hasConcept C150194340 @default.
• W2094115819 hasConcept C2776202225 @default.
• W2094115819 hasConcept C2776262904 @default.
• W2094115819 hasConcept C2776694085 @default.
• W2094115819 hasConcept C2776715637 @default.
• W2094115819 hasConcept C2778305200 @default.
• W2094115819 hasConcept C2781303535 @default.
• W2094115819 hasConcept C41091548 @default.
• W2094115819 hasConcept C502942594 @default.
• W2094115819 hasConcept C54355233 @default.
• W2094115819 hasConcept C64927066 @default.
• W2094115819 hasConcept C81885089 @default.
• W2094115819 hasConcept C86803240 @default.
• W2094115819 hasConcept C98274493 @default.
• W2094115819 hasConceptScore W2094115819C104317684 @default.
• W2094115819 hasConceptScore W2094115819C127716648 @default.
• W2094115819 hasConceptScore W2094115819C150194340 @default.
• W2094115819 hasConceptScore W2094115819C2776202225 @default.
• W2094115819 hasConceptScore W2094115819C2776262904 @default.
• W2094115819 hasConceptScore W2094115819C2776694085 @default.
• W2094115819 hasConceptScore W2094115819C2776715637 @default.
• W2094115819 hasConceptScore W2094115819C2778305200 @default.
• W2094115819 hasConceptScore W2094115819C2781303535 @default.
• W2094115819 hasConceptScore W2094115819C41091548 @default.
• W2094115819 hasConceptScore W2094115819C502942594 @default.
• W2094115819 hasConceptScore W2094115819C54355233 @default.
• W2094115819 hasConceptScore W2094115819C64927066 @default.
• W2094115819 hasConceptScore W2094115819C81885089 @default.
• W2094115819 hasConceptScore W2094115819C86803240 @default.
• W2094115819 hasConceptScore W2094115819C98274493 @default.
• W2094115819 hasIssue "7" @default.

• next