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- W2094142479 abstract "It all seemed so simple. We envisaged that we would be able to predict how our patient would respond to a drug by doing simple genetic tests. We could then tailor drug administration to the test result. Those with insensitive receptors would receive a higher dose or different drug. Risk of toxicity would be reduced by identifying slow metabolizers. Ultimately, the drugs would be more effective and have fewer side effects, and patient outcomes would be improved. Unfortunately, although we may ultimately achieve this goal, we are not there, yet, at least not for opioids and their use for neuraxial labor analgesia. In fact, as the story unfolds and more research is published in this area, it may seem, at least to the average clinician, as though our understanding of the subject is becoming more muddled and confused, rather than less." @default.
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- W2094142479 date "2012-04-01" @default.
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- W2094142479 title "The promise of pharmacogenetics in labor analgesia…tantalizing, but not there yet" @default.
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- W2094142479 doi "https://doi.org/10.1016/j.ijoa.2012.02.003" @default.
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