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- W2094155504 abstract "The intracellular compartmentation of Ap4A in various growth and cell-cycle stages in mammalian cells was studied by applying a non-aqueous extraction procedure for cell nuclei. In both slowly and in exponentially growing Ehrlich ascites tumour cells from random cultures, more than 75% of the whole cellular Ap4A content is localized in the nuclei. In G1 and early S-phase cells of synchronized baby hamster kidney (BHK) fibroblast cultures, approx. 90% of the intracellular Ap4A pool is confined to the nuclear compartment. In contrast, Ap4A is distributed to nearly equal amounts between cytoplasm and nuclei during mid-S phase. After transition through the S phase, increasing proportions of Ap4A (78% 18 h and 96% 22 h after serum replenishing, respectively) are again localized in the nuclear compartment." @default.
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- W2094155504 date "1986-08-01" @default.
- W2094155504 modified "2023-09-29" @default.
- W2094155504 title "Diadenosine tetraphosphate (Ap4A) is compartmentalized in nuclei of mammalian cells" @default.
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- W2094155504 doi "https://doi.org/10.1016/0014-4827(86)90607-5" @default.
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