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- W2094156095 abstract "An early sign of human myoblast commitment to fusion is the expression of a non‐inactivating delayed rectifier K + current, I K(NI) , and an associated membrane potential hyperpolarization. We have isolated the full‐length coding region of a human ether‐a‐go‐go K + channel (h‐ eag ) from myoblasts undergoing differentiation. The h‐ eag gene was localized to chromosome 1q32–41, and is expressed as a ∼9 kb transcript in myogenic cells and in adult brain tissue. Forced expression of h‐ eag in undifferentiated myoblasts generates a current with remarkable similarity to I K(NI) indicating that h‐ eag constitutes the channel responsible for this current in vivo." @default.
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- W2094156095 date "1998-08-28" @default.
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- W2094156095 title "Cloning of a human <i>ether‐a‐go‐go</i> potassium channel expressed in myoblasts at the onset of fusion" @default.
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- W2094156095 doi "https://doi.org/10.1016/s0014-5793(98)00973-9" @default.
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