Matches in SemOpenAlex for { <https://semopenalex.org/work/W2094213154> ?p ?o ?g. }
- W2094213154 endingPage "162" @default.
- W2094213154 startingPage "154" @default.
- W2094213154 abstract "The neuromodulatory effects of cannabinoids in the central nervous system have mainly been associated with G-protein coupled cannabinoid receptor (CB1R) mediated inhibition of voltage-gated calcium channels (VGCCs). Numerous studies show, however, that cannabinoids can also modulate VGCCs independent of CB1R activation. Nevertheless, despite the fact that endocannabinoids have a nearly equal efficacy for direct and CB1R-mediated effects on VGCC, the role of the direct cannabinoid-VGCC interaction has been largely underestimated. In this review, we summarize recent studies on the modulation of different types of VGCCs by cannabinoids, highlight the evidence for and implications of the CB1R-independent modulation, and put forward the concept, that direct interaction of cannabinoids and VGCCs is as important in regulation of VGCCs function as the CB1R-mediated effects." @default.
- W2094213154 created "2016-06-24" @default.
- W2094213154 creator A5011370949 @default.
- W2094213154 creator A5050027665 @default.
- W2094213154 creator A5063060081 @default.
- W2094213154 creator A5068235733 @default.
- W2094213154 date "2009-09-01" @default.
- W2094213154 modified "2023-10-17" @default.
- W2094213154 title "Dual modulation of CNS voltage-gated calcium channels by cannabinoids: Focus on CB1 receptor-independent effects" @default.
- W2094213154 cites W1253199717 @default.
- W2094213154 cites W1529806277 @default.
- W2094213154 cites W1591647183 @default.
- W2094213154 cites W1617914701 @default.
- W2094213154 cites W1639584526 @default.
- W2094213154 cites W1654380405 @default.
- W2094213154 cites W1663380562 @default.
- W2094213154 cites W1670633125 @default.
- W2094213154 cites W1830687359 @default.
- W2094213154 cites W1839710879 @default.
- W2094213154 cites W1931308193 @default.
- W2094213154 cites W1949541784 @default.
- W2094213154 cites W1966235145 @default.
- W2094213154 cites W1968911801 @default.
- W2094213154 cites W1972975528 @default.
- W2094213154 cites W1973774852 @default.
- W2094213154 cites W1976813870 @default.
- W2094213154 cites W1980325410 @default.
- W2094213154 cites W1981921792 @default.
- W2094213154 cites W1986973205 @default.
- W2094213154 cites W1989073099 @default.
- W2094213154 cites W1989915314 @default.
- W2094213154 cites W1997254505 @default.
- W2094213154 cites W2003945052 @default.
- W2094213154 cites W2003978459 @default.
- W2094213154 cites W2007265649 @default.
- W2094213154 cites W2008706909 @default.
- W2094213154 cites W2010651242 @default.
- W2094213154 cites W2011161535 @default.
- W2094213154 cites W2012134063 @default.
- W2094213154 cites W2017842657 @default.
- W2094213154 cites W2018953051 @default.
- W2094213154 cites W2022309859 @default.
- W2094213154 cites W2025367674 @default.
- W2094213154 cites W2029468394 @default.
- W2094213154 cites W2035428388 @default.
- W2094213154 cites W2037426857 @default.
- W2094213154 cites W2052006707 @default.
- W2094213154 cites W2055705346 @default.
- W2094213154 cites W2056268328 @default.
- W2094213154 cites W2056312362 @default.
- W2094213154 cites W2057012057 @default.
- W2094213154 cites W2057665893 @default.
- W2094213154 cites W2062614777 @default.
- W2094213154 cites W2066067166 @default.
- W2094213154 cites W2066960861 @default.
- W2094213154 cites W2067338456 @default.
- W2094213154 cites W2067777963 @default.
- W2094213154 cites W2070135811 @default.
- W2094213154 cites W2079071356 @default.
- W2094213154 cites W2079785767 @default.
- W2094213154 cites W2082334073 @default.
- W2094213154 cites W2083371696 @default.
- W2094213154 cites W2084766767 @default.
- W2094213154 cites W2085360814 @default.
- W2094213154 cites W2089228070 @default.
- W2094213154 cites W2101072772 @default.
- W2094213154 cites W2107490077 @default.
- W2094213154 cites W2109321075 @default.
- W2094213154 cites W2112213092 @default.
- W2094213154 cites W2112520390 @default.
- W2094213154 cites W2126766019 @default.
- W2094213154 cites W2126836281 @default.
- W2094213154 cites W2128810077 @default.
- W2094213154 cites W2128882835 @default.
- W2094213154 cites W2130408611 @default.
- W2094213154 cites W2130661432 @default.
- W2094213154 cites W2130950257 @default.
- W2094213154 cites W2136273365 @default.
- W2094213154 cites W2140896052 @default.
- W2094213154 cites W2142720747 @default.
- W2094213154 cites W2143470223 @default.
- W2094213154 cites W2151312529 @default.
- W2094213154 cites W2153308867 @default.
- W2094213154 cites W2154061926 @default.
- W2094213154 cites W2154314783 @default.
- W2094213154 cites W2156263771 @default.
- W2094213154 cites W2160691778 @default.
- W2094213154 cites W2161902422 @default.
- W2094213154 cites W2165234601 @default.
- W2094213154 cites W2165892338 @default.
- W2094213154 cites W2166216981 @default.
- W2094213154 cites W2178459653 @default.
- W2094213154 cites W2912991414 @default.
- W2094213154 cites W4241363254 @default.
- W2094213154 cites W4254202750 @default.
- W2094213154 cites W4318599862 @default.
- W2094213154 doi "https://doi.org/10.1016/j.ceca.2009.07.007" @default.
- W2094213154 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19682741" @default.