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• W2094233638 abstract "We developed a small animal embolic stroke model for pharmacological screening trials. Microspheres are injected into the carotid circulations and group embolus dose-response relationships are calculated. Emboli quantity is related to neurologic injury, and small changes in neurologic function are detectable. Rabbits tolerated twice as many microspheres when cyproheptadine-treated after embolization. This demonstrated both the sensitivity of the model and the value of serotonin antagonists in reducing neurological injury." @default.
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• W2094233638 date "1987-12-01" @default.
• W2094233638 modified "2023-10-15" @default.
• W2094233638 title "A model for quantitative evaluation of embolic stroke therapy" @default.
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• W2094233638 doi "https://doi.org/10.1016/0006-8993(87)91613-1" @default.
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