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• W2094248488 endingPage "R118" @default.
• W2094248488 startingPage "R112" @default.
• W2094248488 abstract "The molecular mechanism of muscle contraction is a problem that has exercised biophysicists and biochemists for many years. The common view of the mechanism is embodied in the ‘cross-bridge hypothesis’, in which the relative sliding of thick (myosin) and thin (actin) filaments in cross-striated muscle is brought about by the ‘cross-bridges’, parts of the myosin molecules which protrude from the thick filaments and interact cyclically with the actin filaments, transporting them by a rowing action that is powered by the hydrolysis of ATP. This hypothesis is, however, rather vague on the molecular details of cross-bridge movement and, in the light of the recently determined crystal structures of myosin and actin, it has evolved into the more precise ‘swinging lever-arm hypothesis’." @default.
• W2094248488 created "2016-06-24" @default.
• W2094248488 creator A5052279487 @default.
• W2094248488 date "1997-02-01" @default.
• W2094248488 modified "2023-10-15" @default.
• W2094248488 title "The swinging lever-arm hypothesis of muscle contraction" @default.
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• W2094248488 doi "https://doi.org/10.1016/s0960-9822(06)00051-0" @default.
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