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• W2094289092 abstract "Both acute and chronic inflammatory states are associated with decreased levels of high-density lipoprotein (HDL) cholesterol, yet the underlying mechanism is poorly understood. Endothelial lipase (EL), a recently described member of the triglyceride lipase family, has been shown to be a key enzyme in HDL metabolism. Expression of EL by endothelial cells is upregulated by proinflammatory cytokines and is associated with increased EL-specific triglyceride and phospholipase activity in vitro. Thus, EL may play an important role in lipid metabolism and energy homeostasis in states of acute and chronic inflammation." @default.
• W2094289092 created "2016-06-24" @default.
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• W2094289092 date "2004-07-01" @default.
• W2094289092 modified "2023-10-18" @default.
• W2094289092 title "Endothelial Lipase: A Modulator of Lipoprotein Metabolism Upregulated by Inflammation" @default.
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• W2094289092 doi "https://doi.org/10.1016/j.tcm.2004.03.003" @default.
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