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- W2094389636 abstract "Homogenates of two groups of term umbilical cord (n = 6, 37–40 weeks; n = 6, 38–40 weeks) were separately incubated with [7n-3H]pregnenolone and [1,2,6, 7-3H]dehydroepiandrosterone. Using the reverse-isotope dilution technique, [3H]dehydroepiandrosterone and [3H] testosterone formed from the respective substrates were isolated and characterized. The extent of enzymic conversions were 0.015-0.28% and 0.044-2.2%. These results provide evidence for the metabolic transformation of pregnenolone to testosterone via the Δ5-3β-hydroxy route." @default.
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- W2094389636 date "1992-04-01" @default.
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- W2094389636 title "In vitro formation of testosterone via the Δ5-pathway in the human umbilical cord" @default.
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- W2094389636 doi "https://doi.org/10.1016/0039-128x(92)90007-v" @default.
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