Matches in SemOpenAlex for { <https://semopenalex.org/work/W2094393385> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2094393385 endingPage "403" @default.
- W2094393385 startingPage "397" @default.
- W2094393385 abstract "Chronic oral administration of phenobarbital (PB) and phentyoin was studied in chronically implanted cats. The effects of two dosages (PB, 3 mg/kg and 15 mg/kg; phenytoin, 5 mg/kg and 8 mg/kg) were analyzed with two physiological measures: somatosensory evoked potentials (SEPs) and power spectral analysis of the EEG. The low dosage of PB had no effect on SEPs except those recorded in the mesencephalic reticular formation; high dosage resulted in general SEP attenuation. PB had little effect on the EEG. Phenytoin at both dosages produced three main effects: (1) A negative component in the SEP which appears to be dominant in the dorsal hippocampus was significantly enhanced. (2) EEG changes occurred in the dentatothalamic pathway but not at those electrode locations which recorded fastigiobulbar activity. (3) The EEG changes which did occur were Peak Frequency shifts comparable to those previously reported in humans. The results are interpreted as demonstrating (1) minimal EEG and SEP modifications at the cerebral cortical level due to nontoxic dosages of PB and phenytoin, (2) a selective phenytoin effect on the dentatothalamic outflow of the cerebellum and on the dorsal hippocampus, and (3) a potential usefulness of Peak Frequency analysis as a measure of EEG response to anticonvulsant drugs." @default.
- W2094393385 created "2016-06-24" @default.
- W2094393385 creator A5057025052 @default.
- W2094393385 date "1977-09-01" @default.
- W2094393385 modified "2023-10-16" @default.
- W2094393385 title "Phenobarbital and Phenytoin Effects on Somatosensory Evoked Potentials and Spontaneous EEG in Normal Cat Brain" @default.
- W2094393385 cites W1982607136 @default.
- W2094393385 cites W1990455165 @default.
- W2094393385 cites W2010649380 @default.
- W2094393385 cites W2039235157 @default.
- W2094393385 cites W2047400918 @default.
- W2094393385 cites W2049798730 @default.
- W2094393385 cites W2052597330 @default.
- W2094393385 cites W2066032635 @default.
- W2094393385 cites W2073928756 @default.
- W2094393385 cites W2085962537 @default.
- W2094393385 cites W2410974677 @default.
- W2094393385 cites W4230029783 @default.
- W2094393385 cites W4239738211 @default.
- W2094393385 doi "https://doi.org/10.1111/j.1528-1157.1977.tb04982.x" @default.
- W2094393385 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/891493" @default.
- W2094393385 hasPublicationYear "1977" @default.
- W2094393385 type Work @default.
- W2094393385 sameAs 2094393385 @default.
- W2094393385 citedByCount "15" @default.
- W2094393385 crossrefType "journal-article" @default.
- W2094393385 hasAuthorship W2094393385A5057025052 @default.
- W2094393385 hasConcept C126322002 @default.
- W2094393385 hasConcept C15744967 @default.
- W2094393385 hasConcept C162156334 @default.
- W2094393385 hasConcept C169760540 @default.
- W2094393385 hasConcept C172497186 @default.
- W2094393385 hasConcept C185263204 @default.
- W2094393385 hasConcept C185592680 @default.
- W2094393385 hasConcept C2775858608 @default.
- W2094393385 hasConcept C2778186239 @default.
- W2094393385 hasConcept C2778337148 @default.
- W2094393385 hasConcept C2778655484 @default.
- W2094393385 hasConcept C2778793413 @default.
- W2094393385 hasConcept C2780553513 @default.
- W2094393385 hasConcept C42219234 @default.
- W2094393385 hasConcept C522805319 @default.
- W2094393385 hasConcept C529278444 @default.
- W2094393385 hasConcept C71924100 @default.
- W2094393385 hasConceptScore W2094393385C126322002 @default.
- W2094393385 hasConceptScore W2094393385C15744967 @default.
- W2094393385 hasConceptScore W2094393385C162156334 @default.
- W2094393385 hasConceptScore W2094393385C169760540 @default.
- W2094393385 hasConceptScore W2094393385C172497186 @default.
- W2094393385 hasConceptScore W2094393385C185263204 @default.
- W2094393385 hasConceptScore W2094393385C185592680 @default.
- W2094393385 hasConceptScore W2094393385C2775858608 @default.
- W2094393385 hasConceptScore W2094393385C2778186239 @default.
- W2094393385 hasConceptScore W2094393385C2778337148 @default.
- W2094393385 hasConceptScore W2094393385C2778655484 @default.
- W2094393385 hasConceptScore W2094393385C2778793413 @default.
- W2094393385 hasConceptScore W2094393385C2780553513 @default.
- W2094393385 hasConceptScore W2094393385C42219234 @default.
- W2094393385 hasConceptScore W2094393385C522805319 @default.
- W2094393385 hasConceptScore W2094393385C529278444 @default.
- W2094393385 hasConceptScore W2094393385C71924100 @default.
- W2094393385 hasIssue "3" @default.
- W2094393385 hasLocation W20943933851 @default.
- W2094393385 hasLocation W20943933852 @default.
- W2094393385 hasOpenAccess W2094393385 @default.
- W2094393385 hasPrimaryLocation W20943933851 @default.
- W2094393385 hasRelatedWork W112647218 @default.
- W2094393385 hasRelatedWork W146116879 @default.
- W2094393385 hasRelatedWork W1965016243 @default.
- W2094393385 hasRelatedWork W1967132667 @default.
- W2094393385 hasRelatedWork W1989867719 @default.
- W2094393385 hasRelatedWork W2085529792 @default.
- W2094393385 hasRelatedWork W2094393385 @default.
- W2094393385 hasRelatedWork W2398504645 @default.
- W2094393385 hasRelatedWork W2961578828 @default.
- W2094393385 hasRelatedWork W4312296111 @default.
- W2094393385 hasVolume "18" @default.
- W2094393385 isParatext "false" @default.
- W2094393385 isRetracted "false" @default.
- W2094393385 magId "2094393385" @default.
- W2094393385 workType "article" @default.