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• W2094395812 abstract "Abstract Relatively low levels of tropane alkaloid precursors (tropic acid, tropinone and tropanol) and alkaloids (hyoscyamine and scopolamine) were fed to suspension cultures of Atropa belladonna with repressed alkaloid synthesis to study the transport of these compounds into the cells, to detect possible limiting steps in the biosynthetic pathway and to find ways of stimulating alkaloid production. At the end of the experiments, the cell levels of tropic acid and tropinone had reached the initial nutrient medium concentrations, while cell levels of tropanol, hyoscyamine and scopolamine were high, suggesting an active uptake mechanism. Increased intracellular precursor levels did not forward the biosynthesis of the tropane alkaloids." @default.
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• W2094395812 date "1990-01-01" @default.
• W2094395812 modified "2023-10-14" @default.
• W2094395812 title "Feeding experiments using suspension cultures of Atropa belladonna; limiting steps in the biosynthesis of tropane alkaloids" @default.
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• W2094395812 doi "https://doi.org/10.1016/0031-9422(90)85267-j" @default.
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