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- W2094432705 abstract "HISTIDINEMIA, an inborn error of histidine metabolism, is characterized by the presence of abnormally large amour~ts of histidine in the blood and urine. When the histidine contents of the blood and urine are high, a diagnosis of histidinemia can be confirmed by demonstrating marked deficiency or absence of skin histidase activity. 1 At least 25 mg of stratum corneum is required for spectrophotometric assay of this enzyme, ~ but it is extremely difficult to obtain more than 2 mg of tissue from infants and children. A new sensitive assay method with lC-histidine as substrate was recently developed for use in further studies on histidase in the skin)" @default.
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- W2094432705 date "1980-08-01" @default.
- W2094432705 modified "2023-09-26" @default.
- W2094432705 title "Relationship between skin histidase activity and blood histidine response to histidine intake in patients with histidinemia" @default.
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- W2094432705 doi "https://doi.org/10.1016/s0022-3476(80)80493-8" @default.
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