FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2094446585> ?p ?o ?g. }

• W2094446585 endingPage "1754" @default.
• W2094446585 startingPage "1743" @default.
• W2094446585 abstract "The fragmentation reactions of isomeric dipeptides containing α- and β-alanine residues (αAla-αAla, αAla-βAla, βAla-αAla, and βAla-βAla) were studied using a combination of low-energy and energy resolved collision induced dissociation (CID). Each dipeptide gave a series of different fragment ions, allowing for differentiation. For example, peptides containing an N-terminal β-Ala residue yield a diagnostic imine loss, while lactam ions at m/z 72 are unique to peptides containing β-Ala residues. In addition, MS3 experiments were performed. Structure-specific fragmentation reactions were observed for y1 ions, which help identify the C-terminal residue. The MS3 spectra of the b2 ions are different suggesting they are unique for each peptide. Density functional theory (DFT) calculations predict that b2 ions formed via a neighboring group attack by the amide are thermodynamically favored over those formed via neighboring group attack by the N-terminal amine. Finally, to gain further insight into the unique fragmentation chemistry of the peptides containing an N-terminal β-alanine residue, the fragmentation reactions of protonated β-Ala-NHMe were examined using a combination of experiment and DFT calculations. The relative transition-state energies involved in the four competing losses (NH3, H2O, CH3NH2, and CH2=NH) closely follow the relative abundances of these as determined via CID experiments." @default.
• W2094446585 created "2016-06-24" @default.
• W2094446585 creator A5055577385 @default.
• W2094446585 creator A5068123143 @default.
• W2094446585 creator A5075594544 @default.
• W2094446585 creator A5087347737 @default.
• W2094446585 date "2008-12-01" @default.
• W2094446585 modified "2023-10-18" @default.
• W2094446585 title "Can<i>α</i>- and<i>β</i>-alanine containing peptides Be distinguished based on the CID spectra of their protonated ions?" @default.
• W2094446585 cites W1495926848 @default.
• W2094446585 cites W173701656 @default.
• W2094446585 cites W1839202511 @default.
• W2094446585 cites W1964333199 @default.
• W2094446585 cites W1969743435 @default.
• W2094446585 cites W1970933353 @default.
• W2094446585 cites W1973682902 @default.
• W2094446585 cites W1975798138 @default.
• W2094446585 cites W1983476202 @default.
• W2094446585 cites W1985677015 @default.
• W2094446585 cites W1989648459 @default.
• W2094446585 cites W1993152394 @default.
• W2094446585 cites W1995944305 @default.
• W2094446585 cites W2000798961 @default.
• W2094446585 cites W2004650428 @default.
• W2094446585 cites W2019230599 @default.
• W2094446585 cites W2020020093 @default.
• W2094446585 cites W2025135928 @default.
• W2094446585 cites W2029095221 @default.
• W2094446585 cites W2041753659 @default.
• W2094446585 cites W2054376935 @default.
• W2094446585 cites W2057090139 @default.
• W2094446585 cites W2057706980 @default.
• W2094446585 cites W2062105747 @default.
• W2094446585 cites W2065975257 @default.
• W2094446585 cites W2073401456 @default.
• W2094446585 cites W2078910808 @default.
• W2094446585 cites W2080442075 @default.
• W2094446585 cites W2083158860 @default.
• W2094446585 cites W2083394137 @default.
• W2094446585 cites W2083706976 @default.
• W2094446585 cites W2086501380 @default.
• W2094446585 cites W2086588808 @default.
• W2094446585 cites W2086947766 @default.
• W2094446585 cites W2087963094 @default.
• W2094446585 cites W2088109871 @default.
• W2094446585 cites W2089453634 @default.
• W2094446585 cites W2091682618 @default.
• W2094446585 cites W2096801261 @default.
• W2094446585 cites W2109455023 @default.
• W2094446585 cites W2128708905 @default.
• W2094446585 cites W2129579634 @default.
• W2094446585 cites W2158441984 @default.
• W2094446585 cites W2158844260 @default.
• W2094446585 cites W2160446865 @default.
• W2094446585 cites W2163975486 @default.
• W2094446585 cites W2334928987 @default.
• W2094446585 cites W2952810181 @default.
• W2094446585 cites W4247087974 @default.
• W2094446585 cites W4297193215 @default.
• W2094446585 doi "https://doi.org/10.1016/j.jasms.2008.09.007" @default.
• W2094446585 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18964084" @default.
• W2094446585 hasPublicationYear "2008" @default.
• W2094446585 type Work @default.
• W2094446585 sameAs 2094446585 @default.
• W2094446585 citedByCount "6" @default.
• W2094446585 countsByYear W20944465852014 @default.
• W2094446585 countsByYear W20944465852015 @default.
• W2094446585 countsByYear W20944465852022 @default.
• W2094446585 crossrefType "journal-article" @default.
• W2094446585 hasAuthorship W2094446585A5055577385 @default.
• W2094446585 hasAuthorship W2094446585A5068123143 @default.
• W2094446585 hasAuthorship W2094446585A5075594544 @default.
• W2094446585 hasAuthorship W2094446585A5087347737 @default.
• W2094446585 hasConcept C102931765 @default.
• W2094446585 hasConcept C111919701 @default.
• W2094446585 hasConcept C131779359 @default.
• W2094446585 hasConcept C145148216 @default.
• W2094446585 hasConcept C147597530 @default.
• W2094446585 hasConcept C152365726 @default.
• W2094446585 hasConcept C161790260 @default.
• W2094446585 hasConcept C162356407 @default.
• W2094446585 hasConcept C176107965 @default.
• W2094446585 hasConcept C178790620 @default.
• W2094446585 hasConcept C185592680 @default.
• W2094446585 hasConcept C191015642 @default.
• W2094446585 hasConcept C2776573223 @default.
• W2094446585 hasConcept C2778439535 @default.
• W2094446585 hasConcept C2779138802 @default.
• W2094446585 hasConcept C2779281246 @default.
• W2094446585 hasConcept C2779856020 @default.
• W2094446585 hasConcept C2781338088 @default.
• W2094446585 hasConcept C30095370 @default.
• W2094446585 hasConcept C31827203 @default.
• W2094446585 hasConcept C41008148 @default.
• W2094446585 hasConcept C43617362 @default.
• W2094446585 hasConcept C515207424 @default.
• W2094446585 hasConcept C55493867 @default.
• W2094446585 hasConcept C71240020 @default.

• next