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• W2094451441 abstract "VLBW infants are at high risk for CP and are often followed in multidisciplinary high risk infant clinics. We studied the ability of neuromotor assessments, performed in such a clinic at one year of age(adjusted for prematurity), to predict the presence or absence of CP after three years of age, in a geographically based sample of VLBW infants. The study sample included 371 consecutive infants, with birth weight 500 to 1500 grams, born 7/1/88 to 6/30/93 to mothers residing in a six-county region in which our medical center is the only provider of tertiary care. These infants underwent neurological examination and developmental testing at one year adjusted age, at which time 21 infants were classified as having definite CP, 10, as having possible CP, and 340, as being free fromsigns of CP. Status after age three was assessed July-August, 1996, when the infants were three to eight years old. Records from our CP clinic were used to ascertain whether infants diagnosed with CP at one year continued to have signs of CP beyond age three. Telephone calls, followed by a mailed questionnaire to families not available by phone, were used to ascertain the status, at age 3 to 8 years, of infants who at one year of age had either possible CP no CP. Parents were asked whether, after one year of age, their child had been diagnosed with CP, had worn leg braces or splints, or had received treatment by a physical therapist or orthopedic surgeon. Sixteen of the 21 (76%) infants with CP at one year have been followed in our CP clinic; in all 16 the diagnosis of cerebral palsy has persisted beyond age three. Follow-up after age three(telephone or postal) was obtained for 7 (70%) infants with possible CP and 166 (49%) infants without signs of CP at age one. The diagnosis of CP had been made after age three in 2 infants (29% of the 7 contacted) who at one year of age were diagnosed with possible CP, and 4 infants (3% of the 166 contacted) who at one year of age were thought to be free from CP. We conclude that the accuracy of a mutidisciplinary evaluation at one year adjusted age, for predicting CP after age three, is high (positive predictive value = 100%; negative predictive value=97%). Equally important, our findings suggest that approximately one quarter of cases of CP in VLBW infants will be missed if follow-up does not extend beyond one year adjusted age." @default.
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• W2094451441 date "1998-04-01" @default.
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• W2094451441 title "Accuracy of Examination at One Year Adjusted Age in Very Low Birth Weight(VLBW) Infants for Predicting the Presence or Absence of Cerebral Palsy (CP) After Age 3 • 1308" @default.
• W2094451441 doi "https://doi.org/10.1203/00006450-199804001-01329" @default.
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