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• W2094482422 abstract "The timeliness of a review of the neuropathology ofhuman spinal cord injury (SCI) centres on theincreasing interest in central axonal regeneration inthe search for a ‘cure’ of spinal paralysis. Neuropathol-ogy contributes to this end by describing the nature ofthe disorder to be cured. More broadly a knowledge ofthe neuropathology underlying SCI is essential also forthe clinician responsible for management of the patientas well as the neuroscientist working on SCI. There hasbeen spectacular progress in neurobiology in recentyears with CNS repair and regeneration now reportedby many centres. However, in order for thesediscoveries to be applied to human SCI an apprecia-tion of the neuropathology is required. The neurobiol-ogist must be aware of the nature of the condition tobe cured for the research to be relevant. Furthermore,before the experimental findings may be applied to thepatient it must be shown that the reactions to injuryare comparable in each. An outline of recent advancesin the neurobiology of experimental SCI is thereforeincluded in this review in order to bridge the gapbetween human SCI and the experimental models.Most importantly the insight provided by the complex-ity of the problem of finding a cure serves to informthose waiting for this to occur to be realistic in theirexpectations." @default.
• W2094482422 created "2016-06-24" @default.
• W2094482422 creator A5020119695 @default.
• W2094482422 date "1999-01-29" @default.
• W2094482422 modified "2023-10-06" @default.
• W2094482422 title "The applied neuropathology of human spinal cord injury" @default.
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• W2094482422 doi "https://doi.org/10.1038/sj.sc.3100807" @default.
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