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• W2094489596 abstract "Three-dimensional (3D) twisted projection imaging (TPI) trajectory has a unique advantage in sodium ((23)Na) imaging on clinical MRI scanners at 1.5 or 3 T, generating a high signal-to-noise ratio (SNR) with a short acquisition time (approximately 10 min). Parallel imaging with an array of coil elements transits SNR benefits from small coil elements to acquisition efficiency by sampling partial k-space. This study investigates the feasibility of parallel sodium imaging with emphases on SNR and acceleration benefits provided by the 3D TPI trajectory. Computer simulations were used to find available acceleration factors and noise amplification. Human head studies were performed on clinical 1.5/3-T scanners with four-element coil arrays to verify simulation outcomes. In in vivo studies, proton ((1)H) data, however, were acquired for concept-proof purpose. The sensitivity encoding (SENSE) method with the conjugate gradient algorithm was used to reconstruct images from accelerated TPI-SENSE data sets. Self-calibration was employed to estimate coil sensitivities. Noise amplification in TPI-SENSE was evaluated using multiple noise trials. It was found that the acceleration factor was as high as 5.53 (corresponding to acceleration number 2 x 3, ring-by-rotation), with a small image error of 6.9% when TPI projections were reduced in both polar (ring) and azimuthal (rotation) directions. The average noise amplification was as low as 98.7%, or 27% lower than Cartesian SENSE at that acceleration factor. The 3D nature of both TPI trajectory and coil sensitivities might be responsible for the high acceleration and low noise amplification. Consequently, TPI-SENSE may have potential advantages for parallel sodium imaging." @default.
• W2094489596 created "2016-06-24" @default.
• W2094489596 creator A5010298813 @default.
• W2094489596 creator A5067912070 @default.
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• W2094489596 date "2009-06-01" @default.
• W2094489596 modified "2023-09-25" @default.
• W2094489596 title "Parallel imaging with 3D TPI trajectory: SNR and acceleration benefits" @default.
• W2094489596 cites W1981562561 @default.
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• W2094489596 doi "https://doi.org/10.1016/j.mri.2008.10.008" @default.
• W2094489596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19110392" @default.
• W2094489596 hasPublicationYear "2009" @default.
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