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- W2094540216 abstract "Letters and Corrections1 January 1986Thrombocytopenia and SulindacGEORGE N. KARACHALIOS, M.D., JOHN G. PARIGORAKIS, M.D.GEORGE N. KARACHALIOS, M.D.Search for more papers by this author, JOHN G. PARIGORAKIS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-104-1-128_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Sulindac is a nonsteroidal anti-inflammatory and analgesic drug that is now used extensively in the treatment of various forms of rheumatic disease. Several reports of adverse reactions, such as hepatotoxicity, Stevens-Johnson syndrome, aplastic anemia, and hypersensitivity, have been noted (1, 2). We report a case in which a severe thrombocytopenic reaction was associated with the use of sulindac.A 67-year-old woman presented with a painful shoulder and right knee in March 1982. History and physical findings were consistent with osteoarthritis, and treatment was started with diclofenac sodium for 1 month without effect. On 15 May, diclofenac sodium...References1. PARKSPECTORHEADSTREAMGOLDBERG GRTM. Serious adverse reactions associated with sulindac. Arch Intern Med. 1982;142:1292-4. CrossrefMedlineGoogle Scholar2. SMITHLINDBERG FP. Life-threatening hypersensitivity to sulindac. JAMA. 1980;244:269-70. CrossrefMedlineGoogle Scholar3. ROSENBAUMO'CONNOR JM. Thrombocytopenia associated with sulindac. Arthritis Rheum. 1981;24:752-3. CrossrefMedlineGoogle Scholar4. SIMONMILLS LJ. Nonsteroidal anti-inflammatory drugs. N Engl J Med. 1980;202:1179-85. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Kalamata General Hospital Kalamata Greece PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByDiclofenac-induced thrombocytopenic purpura with renal and hepatic involvement 1 January 1986Volume 104, Issue 1Page: 128-128KeywordsAdverse reactionsAnalgesicsAplastic anemiaHypersensitivityKneesOsteoarthritisShouldersSodium Issue Published: 1 January 1986 PDF DownloadLoading ..." @default.
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- W2094540216 title "Thrombocytopenia and Sulindac" @default.
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