Matches in SemOpenAlex for { <https://semopenalex.org/work/W2094550927> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2094550927 endingPage "555" @default.
- W2094550927 startingPage "549" @default.
- W2094550927 abstract "1. Changes in cytosolic free Ca2+ concentration ([Ca2+]i) induced by noradrenaline (NA) and ATP were investigated using indo-1 microspectrofluorimetry in single smooth muscle cells of rat portal vein. 2. Activation of P2x-purinoceptors by ATP (10 microM) increased [Ca2+]i from 92 +/- 7 nM (n = 18) to 557 +/- 30 nM (n = 11). In the presence of NA (10 microM), the ATP-induced rise in [Ca2+]i was reduced to 23.6 +/- 1.5% (n = 7) of the control response (in the absence of NA). 3. Tetracaine (10 microM to 2 mM) inhibited in a concentration-dependent manner the Ca(2+)-induced Ca2+ release (CICR) evoked by 5 mM caffeine. In the presence of 1 mM tetracaine, the rise in [Ca2+]i induced by ATP (10(-8)-10(-4) M) was strongly inhibited. A tetracaine-resistant rise in [Ca2+]i, corresponding to 26.4 +/- 2.3% (n = 14) of control values, was recorded in response to 10 microM ATP. 4. The amplitude of the NA-induced [Ca2+]i rise depended on NA concentrations (10(-8)-10(-5) M) and was not modified by tetracaine (1 mM). 5. This study suggests that Ca2+ ions released through the InsP3 receptor-channel upon NA application do not activate CICR and the InsP3- and Ca(2+)-sensitive Ca2+ store appears to represent, at least functionally, a single releasable Ca2+ pool." @default.
- W2094550927 created "2016-06-24" @default.
- W2094550927 creator A5024595810 @default.
- W2094550927 creator A5086228247 @default.
- W2094550927 date "1995-05-01" @default.
- W2094550927 modified "2023-10-18" @default.
- W2094550927 title "Release of Ca2+ by noradrenaline and ATP from the same Ca2+ store sensitive to both InsP3 and Ca2+ in rat portal vein myocytes." @default.
- W2094550927 cites W1523078822 @default.
- W2094550927 cites W1546706272 @default.
- W2094550927 cites W1956859188 @default.
- W2094550927 cites W1996024251 @default.
- W2094550927 cites W1997816574 @default.
- W2094550927 cites W2001498679 @default.
- W2094550927 cites W2020778098 @default.
- W2094550927 cites W2021487722 @default.
- W2094550927 cites W2021847777 @default.
- W2094550927 cites W2033465778 @default.
- W2094550927 cites W2033792131 @default.
- W2094550927 cites W2055126090 @default.
- W2094550927 cites W2057869841 @default.
- W2094550927 cites W2085276868 @default.
- W2094550927 cites W2109169834 @default.
- W2094550927 cites W2141260882 @default.
- W2094550927 cites W2153598979 @default.
- W2094550927 cites W311879533 @default.
- W2094550927 doi "https://doi.org/10.1113/jphysiol.1995.sp020685" @default.
- W2094550927 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1157942" @default.
- W2094550927 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7623275" @default.
- W2094550927 hasPublicationYear "1995" @default.
- W2094550927 type Work @default.
- W2094550927 sameAs 2094550927 @default.
- W2094550927 citedByCount "35" @default.
- W2094550927 countsByYear W20945509272012 @default.
- W2094550927 countsByYear W20945509272016 @default.
- W2094550927 countsByYear W20945509272019 @default.
- W2094550927 countsByYear W20945509272020 @default.
- W2094550927 crossrefType "journal-article" @default.
- W2094550927 hasAuthorship W2094550927A5024595810 @default.
- W2094550927 hasAuthorship W2094550927A5086228247 @default.
- W2094550927 hasBestOaLocation W20945509271 @default.
- W2094550927 hasConcept C12554922 @default.
- W2094550927 hasConcept C126322002 @default.
- W2094550927 hasConcept C134018914 @default.
- W2094550927 hasConcept C178790620 @default.
- W2094550927 hasConcept C181199279 @default.
- W2094550927 hasConcept C185592680 @default.
- W2094550927 hasConcept C2778455913 @default.
- W2094550927 hasConcept C2778500429 @default.
- W2094550927 hasConcept C2780149897 @default.
- W2094550927 hasConcept C42219234 @default.
- W2094550927 hasConcept C519063684 @default.
- W2094550927 hasConcept C55493867 @default.
- W2094550927 hasConcept C71924100 @default.
- W2094550927 hasConcept C86803240 @default.
- W2094550927 hasConcept C98539663 @default.
- W2094550927 hasConceptScore W2094550927C12554922 @default.
- W2094550927 hasConceptScore W2094550927C126322002 @default.
- W2094550927 hasConceptScore W2094550927C134018914 @default.
- W2094550927 hasConceptScore W2094550927C178790620 @default.
- W2094550927 hasConceptScore W2094550927C181199279 @default.
- W2094550927 hasConceptScore W2094550927C185592680 @default.
- W2094550927 hasConceptScore W2094550927C2778455913 @default.
- W2094550927 hasConceptScore W2094550927C2778500429 @default.
- W2094550927 hasConceptScore W2094550927C2780149897 @default.
- W2094550927 hasConceptScore W2094550927C42219234 @default.
- W2094550927 hasConceptScore W2094550927C519063684 @default.
- W2094550927 hasConceptScore W2094550927C55493867 @default.
- W2094550927 hasConceptScore W2094550927C71924100 @default.
- W2094550927 hasConceptScore W2094550927C86803240 @default.
- W2094550927 hasConceptScore W2094550927C98539663 @default.
- W2094550927 hasIssue "3" @default.
- W2094550927 hasLocation W20945509271 @default.
- W2094550927 hasLocation W20945509272 @default.
- W2094550927 hasLocation W20945509273 @default.
- W2094550927 hasOpenAccess W2094550927 @default.
- W2094550927 hasPrimaryLocation W20945509271 @default.
- W2094550927 hasRelatedWork W2003842308 @default.
- W2094550927 hasRelatedWork W2024489118 @default.
- W2094550927 hasRelatedWork W2064236298 @default.
- W2094550927 hasRelatedWork W2070228801 @default.
- W2094550927 hasRelatedWork W2093566267 @default.
- W2094550927 hasRelatedWork W2095093072 @default.
- W2094550927 hasRelatedWork W2135866758 @default.
- W2094550927 hasRelatedWork W2156876238 @default.
- W2094550927 hasRelatedWork W2257298974 @default.
- W2094550927 hasRelatedWork W2426789235 @default.
- W2094550927 hasVolume "484" @default.
- W2094550927 isParatext "false" @default.
- W2094550927 isRetracted "false" @default.
- W2094550927 magId "2094550927" @default.
- W2094550927 workType "article" @default.