FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2094552165> ?p ?o ?g. }

• W2094552165 endingPage "291" @default.
• W2094552165 startingPage "281" @default.
• W2094552165 abstract "It has been believed that clonal propagation by asexual reproduction has serious disadvantages for long-term survival, because asexual reproduction seems not to remove harmful mutations, it seems not to give rise to genetic variations upon which evolution depends and it seems not to reset cell aging. In this article, we re-consider those arguments, by reviewing asexual reproduction of the tunicate, Polyandrocarpa misakiensis. Tracer experiments of bud formation and growth using morphological and chimeric phenotypes showed that the parental epithelial tissues surrounding the bud primordium do not enter the growing bud. It is possible, therefore, to assume that budding involves the purge of a large number of parental somatic cells and tissues. Unlike sexuals, asexuals do not carry out meiotic recombination nor gene shuffling that are two major sources of genetic variation, but we can show that in P. misakiensis at least two genes have significant redundancy and genetic variation even in a clonal colony. Telomerase expressed in germlines is thought to reset the molecular clock executed by telomere shortening. In our Polyandrocarpa cDNA projects, four out of about 2,000 cDNAs examined were matched with retroviral reverse transcriptase that is the catalytic subunit of telomerase, suggesting that telomerase might work in asexual reproduction. In P. misakiensis, dedifferentiation system is used to make new asexual generations. TC14 lectin plays an important role in the maintenance of multipotent but differentiated state of the formative tissue. It is antagonized by tunicate serine protease (TRAMP) that has striking mitogenic and dedifferentiation-inducing activities on the multipotent cells. This system would serve to delay aging of somatic cells. In conclusion, empirical arguments that asexual reproduction is disadvantageous to long-term life do not appear to be tenable to budding of P. misakiensis." @default.
• W2094552165 created "2016-06-24" @default.
• W2094552165 creator A5013791617 @default.
• W2094552165 creator A5034537316 @default.
• W2094552165 date "2000-04-01" @default.
• W2094552165 modified "2023-09-27" @default.
• W2094552165 title "Advantage or Disadvantage: Is Asexual Reproduction Beneficial to Survival of the Tunicate, Polyandrocarpa misakiensis" @default.
• W2094552165 cites W1487014009 @default.
• W2094552165 cites W1491251440 @default.
• W2094552165 cites W1513934425 @default.
• W2094552165 cites W1550165896 @default.
• W2094552165 cites W1554038804 @default.
• W2094552165 cites W1556517582 @default.
• W2094552165 cites W1561255328 @default.
• W2094552165 cites W1566245339 @default.
• W2094552165 cites W1588064449 @default.
• W2094552165 cites W1641544182 @default.
• W2094552165 cites W1670027677 @default.
• W2094552165 cites W1670575907 @default.
• W2094552165 cites W1747710289 @default.
• W2094552165 cites W1822218099 @default.
• W2094552165 cites W1831776229 @default.
• W2094552165 cites W1839838630 @default.
• W2094552165 cites W1844635201 @default.
• W2094552165 cites W1857512534 @default.
• W2094552165 cites W1911318042 @default.
• W2094552165 cites W1923477899 @default.
• W2094552165 cites W1941813041 @default.
• W2094552165 cites W1956253188 @default.
• W2094552165 cites W1966145755 @default.
• W2094552165 cites W1971617897 @default.
• W2094552165 cites W1976209293 @default.
• W2094552165 cites W1977117310 @default.
• W2094552165 cites W1977852064 @default.
• W2094552165 cites W1979151631 @default.
• W2094552165 cites W1981245106 @default.
• W2094552165 cites W1983673827 @default.
• W2094552165 cites W1985218912 @default.
• W2094552165 cites W1991595275 @default.
• W2094552165 cites W1992525863 @default.
• W2094552165 cites W1993991084 @default.
• W2094552165 cites W2000971601 @default.
• W2094552165 cites W2004561527 @default.
• W2094552165 cites W2004778468 @default.
• W2094552165 cites W2015037479 @default.
• W2094552165 cites W2017658415 @default.
• W2094552165 cites W2018569042 @default.
• W2094552165 cites W2022507419 @default.
• W2094552165 cites W2024265240 @default.
• W2094552165 cites W2024384036 @default.
• W2094552165 cites W2026069119 @default.
• W2094552165 cites W2028769233 @default.
• W2094552165 cites W2035733413 @default.
• W2094552165 cites W2039316880 @default.
• W2094552165 cites W2043204829 @default.
• W2094552165 cites W2043693673 @default.
• W2094552165 cites W2046037221 @default.
• W2094552165 cites W2049462421 @default.
• W2094552165 cites W2050199039 @default.
• W2094552165 cites W2051595973 @default.
• W2094552165 cites W2053822186 @default.
• W2094552165 cites W2056326368 @default.
• W2094552165 cites W2058197513 @default.
• W2094552165 cites W2060985723 @default.
• W2094552165 cites W2062447460 @default.
• W2094552165 cites W2065757328 @default.
• W2094552165 cites W2072850212 @default.
• W2094552165 cites W2074607326 @default.
• W2094552165 cites W2081327669 @default.
• W2094552165 cites W2085545117 @default.
• W2094552165 cites W2088672106 @default.
• W2094552165 cites W2089402463 @default.
• W2094552165 cites W2094218023 @default.
• W2094552165 cites W2101502555 @default.
• W2094552165 cites W2106291988 @default.
• W2094552165 cites W2106967153 @default.
• W2094552165 cites W2108252995 @default.
• W2094552165 cites W2108482850 @default.
• W2094552165 cites W2118916608 @default.
• W2094552165 cites W2122740168 @default.
• W2094552165 cites W2125572357 @default.
• W2094552165 cites W2128023856 @default.
• W2094552165 cites W212823520 @default.
• W2094552165 cites W2135123683 @default.
• W2094552165 cites W2135817668 @default.
• W2094552165 cites W2139406125 @default.
• W2094552165 cites W2140724459 @default.
• W2094552165 cites W2142812124 @default.
• W2094552165 cites W2153824299 @default.
• W2094552165 cites W2161819299 @default.
• W2094552165 cites W2169952584 @default.
• W2094552165 cites W2185118823 @default.
• W2094552165 cites W2209731836 @default.
• W2094552165 cites W2241698229 @default.
• W2094552165 cites W2258340364 @default.
• W2094552165 cites W2301185024 @default.
• W2094552165 cites W2301822836 @default.
• W2094552165 cites W2404295092 @default.

• next