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• W2094560520 abstract "Inflammatory brain diseases such as multiple sclerosis (MS) include hyperactivation of the coagulation pathway which includes thrombin. In the experimental autoimmune encephalomyelitis (EAE) model we have found significantly higher levels of thrombin inhibitors which include the very early elevation of protease nexin 1. The physiological importance of excess thrombin in neural tissue is demonstrated by recent experiments which link thrombin with conduction block in the sciatic nerve." @default.
• W2094560520 created "2016-06-24" @default.
• W2094560520 creator A5072166912 @default.
• W2094560520 date "2006-10-01" @default.
• W2094560520 modified "2023-10-05" @default.
• W2094560520 title "Thrombin in inflammatory brain diseases" @default.
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• W2094560520 doi "https://doi.org/10.1016/j.autrev.2006.02.011" @default.
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