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- W2094580892 abstract "Bioassay-guided fractionation of the organic extract derived from the terrestrial fungus Penicillium coalescens led to the isolation of the known mycotoxin (−)-botryodiplodin (1) and eight new structurally related analogues (2−9). The structures of the novel compounds were determined by MS and NMR studies, including 1D and 2D NMR. A likely biogenetic pathway from the aldehydic open form of 1 (C7 unit, U1) is proposed for these metabolites. Among all the isolated metabolites, only (−)-1 showed antifungal, antibacterial, and insecticidal activity. This latter activity appears to be a new property attributed to (−)-1. Keywords: Penicillium coalescens; (−)-botryodiplodin; natural products; fungal metabolites; antifungal; antibacterial; insecticidal activity; Oncopeltus fasciatus; Ceratitis capitata" @default.
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- W2094580892 date "2007-07-12" @default.
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- W2094580892 title "Isolation and Structural Elucidation of Eight New Related Analogues of the Mycotoxin (−)-Botryodiplodin from <i>Penicillium coalescens</i>" @default.
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- W2094580892 doi "https://doi.org/10.1021/jf071568v" @default.
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