Matches in SemOpenAlex for { <https://semopenalex.org/work/W2094609392> ?p ?o ?g. }
- W2094609392 endingPage "148" @default.
- W2094609392 startingPage "140" @default.
- W2094609392 abstract "Sulfated glycosaminoglycans are known to inhibit mammalian acid-active sialidase. Although the inhibition depends clearly on the presence of sulfate groups on these macromolecules, there was no information on the intrinsic inhibitory potency of inorganic sulfate. In this study, we demonstrate that inorganic sulfates inhibit acid-active Mu-Neu5Ac sialidase of U937 cells. This inhibition was found to be reversible and it appeared to be of the mixed competitive type. Sulfate-induced inhibition was also observed in other cells as well as with other substrates such as sialyl lactose and bovine mixed brain gangliosides. We conclude that the intrinsic inhibitory potency of sulfate groups may be significantly involved in the inhibition of acid-active sialidase by sulfated glycosaminoglycans. In addition, inorganic sulfate by its apparent potency to selectively inhibit acid sialidases might constitute an interesting tool for the characterisation of the minor forms of sialidases occurring in mammalian cells." @default.
- W2094609392 created "2016-06-24" @default.
- W2094609392 creator A5002232142 @default.
- W2094609392 creator A5020192692 @default.
- W2094609392 creator A5061550954 @default.
- W2094609392 creator A5065246086 @default.
- W2094609392 creator A5075977203 @default.
- W2094609392 creator A5088709075 @default.
- W2094609392 date "1997-03-01" @default.
- W2094609392 modified "2023-09-26" @default.
- W2094609392 title "Inhibition of acid sialidase by inorganic sulfate" @default.
- W2094609392 cites W131247432 @default.
- W2094609392 cites W152915356 @default.
- W2094609392 cites W15346202 @default.
- W2094609392 cites W171794392 @default.
- W2094609392 cites W1748414414 @default.
- W2094609392 cites W1771261141 @default.
- W2094609392 cites W1826433977 @default.
- W2094609392 cites W1894060385 @default.
- W2094609392 cites W1981599361 @default.
- W2094609392 cites W1988306414 @default.
- W2094609392 cites W1993363980 @default.
- W2094609392 cites W1994644330 @default.
- W2094609392 cites W2002486916 @default.
- W2094609392 cites W2042520913 @default.
- W2094609392 cites W2043057817 @default.
- W2094609392 cites W2048173226 @default.
- W2094609392 cites W2049741418 @default.
- W2094609392 cites W2057171278 @default.
- W2094609392 cites W2059260998 @default.
- W2094609392 cites W2063061113 @default.
- W2094609392 cites W2075407653 @default.
- W2094609392 cites W2092901590 @default.
- W2094609392 cites W2128635872 @default.
- W2094609392 cites W2153480853 @default.
- W2094609392 cites W2156932601 @default.
- W2094609392 cites W2170960160 @default.
- W2094609392 cites W2174040273 @default.
- W2094609392 cites W2235940493 @default.
- W2094609392 cites W2329463055 @default.
- W2094609392 cites W23668145 @default.
- W2094609392 cites W953673925 @default.
- W2094609392 doi "https://doi.org/10.1016/s0304-4165(96)00089-x" @default.
- W2094609392 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9101707" @default.
- W2094609392 hasPublicationYear "1997" @default.
- W2094609392 type Work @default.
- W2094609392 sameAs 2094609392 @default.
- W2094609392 citedByCount "5" @default.
- W2094609392 countsByYear W20946093922013 @default.
- W2094609392 crossrefType "journal-article" @default.
- W2094609392 hasAuthorship W2094609392A5002232142 @default.
- W2094609392 hasAuthorship W2094609392A5020192692 @default.
- W2094609392 hasAuthorship W2094609392A5061550954 @default.
- W2094609392 hasAuthorship W2094609392A5065246086 @default.
- W2094609392 hasAuthorship W2094609392A5075977203 @default.
- W2094609392 hasAuthorship W2094609392A5088709075 @default.
- W2094609392 hasConcept C108625454 @default.
- W2094609392 hasConcept C134164806 @default.
- W2094609392 hasConcept C153074725 @default.
- W2094609392 hasConcept C155138218 @default.
- W2094609392 hasConcept C178790620 @default.
- W2094609392 hasConcept C181199279 @default.
- W2094609392 hasConcept C185592680 @default.
- W2094609392 hasConcept C202751555 @default.
- W2094609392 hasConcept C206212055 @default.
- W2094609392 hasConcept C2778343803 @default.
- W2094609392 hasConcept C55493867 @default.
- W2094609392 hasConcept C57992300 @default.
- W2094609392 hasConcept C73695083 @default.
- W2094609392 hasConceptScore W2094609392C108625454 @default.
- W2094609392 hasConceptScore W2094609392C134164806 @default.
- W2094609392 hasConceptScore W2094609392C153074725 @default.
- W2094609392 hasConceptScore W2094609392C155138218 @default.
- W2094609392 hasConceptScore W2094609392C178790620 @default.
- W2094609392 hasConceptScore W2094609392C181199279 @default.
- W2094609392 hasConceptScore W2094609392C185592680 @default.
- W2094609392 hasConceptScore W2094609392C202751555 @default.
- W2094609392 hasConceptScore W2094609392C206212055 @default.
- W2094609392 hasConceptScore W2094609392C2778343803 @default.
- W2094609392 hasConceptScore W2094609392C55493867 @default.
- W2094609392 hasConceptScore W2094609392C57992300 @default.
- W2094609392 hasConceptScore W2094609392C73695083 @default.
- W2094609392 hasIssue "2-3" @default.
- W2094609392 hasLocation W20946093921 @default.
- W2094609392 hasLocation W20946093922 @default.
- W2094609392 hasOpenAccess W2094609392 @default.
- W2094609392 hasPrimaryLocation W20946093921 @default.
- W2094609392 hasRelatedWork W1992742247 @default.
- W2094609392 hasRelatedWork W2000226399 @default.
- W2094609392 hasRelatedWork W2014292534 @default.
- W2094609392 hasRelatedWork W2021568965 @default.
- W2094609392 hasRelatedWork W2033806277 @default.
- W2094609392 hasRelatedWork W2082002860 @default.
- W2094609392 hasRelatedWork W2094609392 @default.
- W2094609392 hasRelatedWork W2391453052 @default.
- W2094609392 hasRelatedWork W3193663583 @default.
- W2094609392 hasRelatedWork W218213081 @default.
- W2094609392 hasVolume "1334" @default.