Matches in SemOpenAlex for { <https://semopenalex.org/work/W2094627574> ?p ?o ?g. }
- W2094627574 endingPage "118" @default.
- W2094627574 startingPage "100" @default.
- W2094627574 abstract "Protagonists of a new scientific era, stem cells are promising tools on which regenerative medicine relies for the treatment of human pathologies. Stem cells can be obtained from various sources, including embryos, fetal tissues, umbilical cord blood, and also terminally differentiated organs. Once forced to expand and differentiate into functional progenies, stem cells may become suitable for cell replacement and tissue engineering. The manipulation and/or stimulation of adult stem cells seems to be particularly promising, as it could improve the endogenous regenerative potential without risks of rejection and overcome the ethical and political issues related to embryonic stem cell research. Stem cells are already leaving the bench and reaching the bedside, despite an incomplete knowledge of the genetic control program driving their fate and plasticity. In gastroenterology and hepatology, the first attempts to translate stem cell basic research into novel therapeutic strategies have been made for the treatment of several disorders, such as inflammatory bowel diseases, diabetes mellitus, celiachy and acute or chronic hepatopaties. Nonetheless, critical aspects need to be further addressed, including the long‐term safety, tolerability and efficacy of cell‐based treatments, as well as their carcinogenic potential. Aim of this review is to summarize the state‐of‐the‐arts on gastrointestinal and hepatic stem cells and on stem cell‐based therapies in gastroenterology and hepatology, highlighting both the benefits and the potential risks of these new tools for the treatment and prevention of human diseases." @default.
- W2094627574 created "2016-06-24" @default.
- W2094627574 creator A5010514963 @default.
- W2094627574 creator A5029268158 @default.
- W2094627574 creator A5031340334 @default.
- W2094627574 creator A5089995050 @default.
- W2094627574 date "2008-01-01" @default.
- W2094627574 modified "2023-09-30" @default.
- W2094627574 title "Stem cell‐based therapy in gastroenterology and hepatology" @default.
- W2094627574 cites W126539919 @default.
- W2094627574 cites W146299810 @default.
- W2094627574 cites W1486751683 @default.
- W2094627574 cites W1518831632 @default.
- W2094627574 cites W1520448761 @default.
- W2094627574 cites W1542326554 @default.
- W2094627574 cites W1550821335 @default.
- W2094627574 cites W1580484253 @default.
- W2094627574 cites W1631250427 @default.
- W2094627574 cites W1719320996 @default.
- W2094627574 cites W1961434948 @default.
- W2094627574 cites W1964825686 @default.
- W2094627574 cites W1965124339 @default.
- W2094627574 cites W1966961395 @default.
- W2094627574 cites W1967703106 @default.
- W2094627574 cites W1968868301 @default.
- W2094627574 cites W1969943647 @default.
- W2094627574 cites W1969986792 @default.
- W2094627574 cites W1970590929 @default.
- W2094627574 cites W1973256561 @default.
- W2094627574 cites W1973278012 @default.
- W2094627574 cites W1975373424 @default.
- W2094627574 cites W1976895035 @default.
- W2094627574 cites W1977480736 @default.
- W2094627574 cites W1982022033 @default.
- W2094627574 cites W1982714656 @default.
- W2094627574 cites W1985760249 @default.
- W2094627574 cites W1986058579 @default.
- W2094627574 cites W1987018141 @default.
- W2094627574 cites W1987964722 @default.
- W2094627574 cites W1988358491 @default.
- W2094627574 cites W1990108083 @default.
- W2094627574 cites W1991068269 @default.
- W2094627574 cites W1991592276 @default.
- W2094627574 cites W1992371996 @default.
- W2094627574 cites W1993065115 @default.
- W2094627574 cites W1993534485 @default.
- W2094627574 cites W1993767935 @default.
- W2094627574 cites W1993902386 @default.
- W2094627574 cites W1994736606 @default.
- W2094627574 cites W1995193342 @default.
- W2094627574 cites W1995649536 @default.
- W2094627574 cites W1996429641 @default.
- W2094627574 cites W2000351395 @default.
- W2094627574 cites W2001046883 @default.
- W2094627574 cites W2001675896 @default.
- W2094627574 cites W2002134865 @default.
- W2094627574 cites W2002391829 @default.
- W2094627574 cites W2002697212 @default.
- W2094627574 cites W2004413672 @default.
- W2094627574 cites W2004727527 @default.
- W2094627574 cites W2004838691 @default.
- W2094627574 cites W2005250390 @default.
- W2094627574 cites W2005849509 @default.
- W2094627574 cites W2009143053 @default.
- W2094627574 cites W2010653264 @default.
- W2094627574 cites W2012668509 @default.
- W2094627574 cites W2012962381 @default.
- W2094627574 cites W2013489743 @default.
- W2094627574 cites W2013568009 @default.
- W2094627574 cites W2014567489 @default.
- W2094627574 cites W2016823790 @default.
- W2094627574 cites W2017200989 @default.
- W2094627574 cites W2017496728 @default.
- W2094627574 cites W2018718092 @default.
- W2094627574 cites W2021542412 @default.
- W2094627574 cites W2022682090 @default.
- W2094627574 cites W2023056020 @default.
- W2094627574 cites W2023105513 @default.
- W2094627574 cites W2023649138 @default.
- W2094627574 cites W2023842938 @default.
- W2094627574 cites W2024835620 @default.
- W2094627574 cites W2025571463 @default.
- W2094627574 cites W2025875442 @default.
- W2094627574 cites W2027802570 @default.
- W2094627574 cites W2028354907 @default.
- W2094627574 cites W2028850760 @default.
- W2094627574 cites W2029231546 @default.
- W2094627574 cites W2029613730 @default.
- W2094627574 cites W2031631150 @default.
- W2094627574 cites W2031675589 @default.
- W2094627574 cites W2032277080 @default.
- W2094627574 cites W2032280075 @default.
- W2094627574 cites W2033045615 @default.
- W2094627574 cites W2034224176 @default.
- W2094627574 cites W2034885353 @default.
- W2094627574 cites W2036795046 @default.
- W2094627574 cites W2037902063 @default.
- W2094627574 cites W2037926016 @default.