FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2094666421> ?p ?o ?g. }

• W2094666421 endingPage "1077" @default.
• W2094666421 startingPage "1072" @default.
• W2094666421 abstract "When found in an otherwise benign biopsy, lobular carcinoma in situ (LCIS) has been associated with an increased risk of development of a subsequent invasive breast carcinoma. However, the association between LCIS and the risk of subsequent local recurrence in patients with infiltrating carcinoma treated with conservative surgery and radiation therapy has received relatively little attention.Between 1968 and 1986, 1625 patients with clinical Stage I-II invasive breast carcinoma were treated at the Joint Center for Radiation Therapy at Harvard Medical School with breast-conserving surgery (CS) and radiation therapy (RT) to a total dose to the primary site of > or =60 grays. Analysis was limited to 1181 patients with infiltrating ductal carcinoma, infiltrating lobular carcinoma, or infiltrating carcinoma with mixed ductal and lobular features who, on review of their histologic slides, had sufficient normal tissue adjacent to the tumor to evaluate for the presence of LCIS and also had a minimum potential follow-up time of 8 years. The median follow-up time was 161 months.One hundred thirty-seven patients (12%) had LCIS either within the tumor or in the macroscopically normal adjacent tissue. The 8-year crude risk of recurrence was not significantly increased for patients with LCIS associated with invasive ductal, invasive lobular, or mixed ductal and lobular carcinoma. Among the 119 patients with associated LCIS adjacent to the tumor, the 8-year rate of local recurrence was 13%, compared with 12% for the 1062 patients without associated LCIS. For the 70 patients with moderate or marked LCIS adjacent to the tumor, the 8-year rate of local recurrence was 13%. The extent of LCIS did not affect the risk of recurrence. The risks of contralateral disease and of distant failure were similarly not affected by the presence or extent of LCIS.Breast-conserving therapy involving limited surgery and radiation therapy is an appropriate method of treating patients with invasive breast carcinoma with or without associated LCIS. Neither the presence nor the extent of LCIS should influence management decisions regarding patients with invasive breast carcinoma. [See editorial counterpoint and reply to counterpoint on pages 978-81 and 982-3, this issue.]" @default.
• W2094666421 created "2016-06-24" @default.
• W2094666421 creator A5006004677 @default.
• W2094666421 creator A5007365512 @default.
• W2094666421 creator A5013474509 @default.
• W2094666421 creator A5021503571 @default.
• W2094666421 creator A5055088975 @default.
• W2094666421 creator A5078561959 @default.
• W2094666421 creator A5085599940 @default.
• W2094666421 creator A5086014533 @default.
• W2094666421 creator A5086891684 @default.
• W2094666421 date "2000-03-01" @default.
• W2094666421 modified "2023-09-30" @default.
• W2094666421 title "The relation between the presence and extent of lobular carcinoma in situ and the risk of local recurrence for patients with infiltrating carcinoma of the breast treated with conservative surgery and radiation therapy" @default.
• W2094666421 cites W1961978963 @default.
• W2094666421 cites W1964299460 @default.
• W2094666421 cites W1983869100 @default.
• W2094666421 cites W1984357287 @default.
• W2094666421 cites W1985831914 @default.
• W2094666421 cites W1990582579 @default.
• W2094666421 cites W2012670228 @default.
• W2094666421 cites W2015993287 @default.
• W2094666421 cites W2045810642 @default.
• W2094666421 cites W2060535188 @default.
• W2094666421 cites W2063327753 @default.
• W2094666421 cites W2089885033 @default.
• W2094666421 cites W2105365583 @default.
• W2094666421 cites W2109030089 @default.
• W2094666421 cites W2141647078 @default.
• W2094666421 cites W2158285353 @default.
• W2094666421 cites W2313004219 @default.
• W2094666421 cites W2327303154 @default.
• W2094666421 cites W4254981757 @default.
• W2094666421 doi "https://doi.org/10.1002/(sici)1097-0142(20000301)88:5<1072::aid-cncr18>3.0.co;2-d" @default.
• W2094666421 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10699897" @default.
• W2094666421 hasPublicationYear "2000" @default.
• W2094666421 type Work @default.
• W2094666421 sameAs 2094666421 @default.
• W2094666421 citedByCount "85" @default.
• W2094666421 countsByYear W20946664212012 @default.
• W2094666421 countsByYear W20946664212013 @default.
• W2094666421 countsByYear W20946664212014 @default.
• W2094666421 countsByYear W20946664212015 @default.
• W2094666421 countsByYear W20946664212016 @default.
• W2094666421 countsByYear W20946664212017 @default.
• W2094666421 countsByYear W20946664212018 @default.
• W2094666421 countsByYear W20946664212020 @default.
• W2094666421 countsByYear W20946664212021 @default.
• W2094666421 countsByYear W20946664212022 @default.
• W2094666421 crossrefType "journal-article" @default.
• W2094666421 hasAuthorship W2094666421A5006004677 @default.
• W2094666421 hasAuthorship W2094666421A5007365512 @default.
• W2094666421 hasAuthorship W2094666421A5013474509 @default.
• W2094666421 hasAuthorship W2094666421A5021503571 @default.
• W2094666421 hasAuthorship W2094666421A5055088975 @default.
• W2094666421 hasAuthorship W2094666421A5078561959 @default.
• W2094666421 hasAuthorship W2094666421A5085599940 @default.
• W2094666421 hasAuthorship W2094666421A5086014533 @default.
• W2094666421 hasAuthorship W2094666421A5086891684 @default.
• W2094666421 hasConcept C121608353 @default.
• W2094666421 hasConcept C126322002 @default.
• W2094666421 hasConcept C126838900 @default.
• W2094666421 hasConcept C142724271 @default.
• W2094666421 hasConcept C143998085 @default.
• W2094666421 hasConcept C2775934546 @default.
• W2094666421 hasConcept C2777546739 @default.
• W2094666421 hasConcept C2777757722 @default.
• W2094666421 hasConcept C2779296616 @default.
• W2094666421 hasConcept C2780862961 @default.
• W2094666421 hasConcept C2781467025 @default.
• W2094666421 hasConcept C509974204 @default.
• W2094666421 hasConcept C530470458 @default.
• W2094666421 hasConcept C71924100 @default.
• W2094666421 hasConceptScore W2094666421C121608353 @default.
• W2094666421 hasConceptScore W2094666421C126322002 @default.
• W2094666421 hasConceptScore W2094666421C126838900 @default.
• W2094666421 hasConceptScore W2094666421C142724271 @default.
• W2094666421 hasConceptScore W2094666421C143998085 @default.
• W2094666421 hasConceptScore W2094666421C2775934546 @default.
• W2094666421 hasConceptScore W2094666421C2777546739 @default.
• W2094666421 hasConceptScore W2094666421C2777757722 @default.
• W2094666421 hasConceptScore W2094666421C2779296616 @default.
• W2094666421 hasConceptScore W2094666421C2780862961 @default.
• W2094666421 hasConceptScore W2094666421C2781467025 @default.
• W2094666421 hasConceptScore W2094666421C509974204 @default.
• W2094666421 hasConceptScore W2094666421C530470458 @default.
• W2094666421 hasConceptScore W2094666421C71924100 @default.
• W2094666421 hasIssue "5" @default.
• W2094666421 hasLocation W20946664211 @default.
• W2094666421 hasLocation W20946664212 @default.
• W2094666421 hasOpenAccess W2094666421 @default.
• W2094666421 hasPrimaryLocation W20946664211 @default.
• W2094666421 hasRelatedWork W1968780402 @default.
• W2094666421 hasRelatedWork W2047900704 @default.
• W2094666421 hasRelatedWork W2060589505 @default.
• W2094666421 hasRelatedWork W2143069457 @default.
• W2094666421 hasRelatedWork W2145470001 @default.
• W2094666421 hasRelatedWork W2164404912 @default.

• next