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- W2094690198 abstract "Abstract Human T lymphocytes infiltrating the liver in chronic active hepatitis B (CAH‐B) and primary biliary cirrhosis were isolated from liver biopsy cores, cloned by limiting dilution technique and expanded in vitro. Phenotypic and functional analysis demonstrates that this tissue infiltrate represents a heterogeneous cell population. However, when compared to peripheral blood lymphocytes of the same patients, a marked enrichment for T8 cytotoxic T cells was found to exist at a local site in both types of chronic liver disease. These data provide support for the notion that liver cell injury in CAH‐B and PBC may be mediated by a common immunologic mechanism likely executed by cells of the T lineage." @default.
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- W2094690198 date "1988-09-01" @default.
- W2094690198 modified "2023-10-17" @default.
- W2094690198 title "Clonal analysis of human T lymphocytes infiltrating the liver in chronic active hepatitis B and primary biliary cirrhosis" @default.
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- W2094690198 doi "https://doi.org/10.1002/eji.1830180922" @default.
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