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- W2094748972 abstract "It is well known that sodium reabsorption and aldosterone play important roles in potassium secretion by the aldosterone-sensitive distal nephron. Sodium- and aldosterone-independent mechanisms also exist. This review focuses on some recent studies that provide novel insights into the sodium- and aldosterone-independent potassium secretion by the aldosterone-sensitive distal nephron. In addition, we discuss a study reporting on the regulation of the mammalian potassium kidney channel ROMK by intracellular and extracellular magnesium, which may be important in the pathogenesis of persistent hypokalemia in patients with concomitant potassium and magnesium deficiency. We also discuss outstanding questions and propose working models for future investigation." @default.
- W2094748972 created "2016-06-24" @default.
- W2094748972 creator A5062825293 @default.
- W2094748972 creator A5075776494 @default.
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- W2094748972 date "2011-04-01" @default.
- W2094748972 modified "2023-10-15" @default.
- W2094748972 title "Recent advances in distal tubular potassium handling" @default.
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- W2094748972 doi "https://doi.org/10.1152/ajprenal.00742.2010" @default.
- W2094748972 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3074996" @default.
- W2094748972 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21270092" @default.
- W2094748972 hasPublicationYear "2011" @default.
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