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• W2094749853 abstract "In the following perspective article, Mellor and Breen provide a counterpoint to a previous perspective on the potential link between ionizing radiation exposure and intervertebral disc degeneration in humans [ [1] Samartzis D. Cheung K. Ionizing radiation exposure and the development of intervertebral disc degeneration in humans: myth or reality. Spine J. 2011; 11: 979-982 Abstract Full Text Full Text PDF PubMed Scopus (10) Google Scholar ]. The previous perspective asked, is this link a myth or reality? It suggested the potential for such a link. Mellor and Breen offer a drastically alternate view, in essence, that the question itself is flawed. To support their perspective, they explain the different units of radiation measurement and their conversion to risk in humans and how this impacts the previous perspective. They explain the variable sensitivity of different body tissues to radiation and highlight that neither human research nor any of the multiple international regulatory agencies have ever suggested that the intervertebral disc is sensitive to radiation. Finally, they claim that it is impossible to predict with any certainty the effects of low-level radiation on the intervertebral discs. In the following perspective article, Mellor and Breen provide a counterpoint to a previous perspective on the potential link between ionizing radiation exposure and intervertebral disc degeneration in humans [ [1] Samartzis D. Cheung K. Ionizing radiation exposure and the development of intervertebral disc degeneration in humans: myth or reality. Spine J. 2011; 11: 979-982 Abstract Full Text Full Text PDF PubMed Scopus (10) Google Scholar ]. The previous perspective asked, is this link a myth or reality? It suggested the potential for such a link. Mellor and Breen offer a drastically alternate view, in essence, that the question itself is flawed. To support their perspective, they explain the different units of radiation measurement and their conversion to risk in humans and how this impacts the previous perspective. They explain the variable sensitivity of different body tissues to radiation and highlight that neither human research nor any of the multiple international regulatory agencies have ever suggested that the intervertebral disc is sensitive to radiation. Finally, they claim that it is impossible to predict with any certainty the effects of low-level radiation on the intervertebral discs. Ionizing radiation exposure and the development of intervertebral disc degeneration in humans: myth or realityThe Spine JournalVol. 11Issue 10PreviewLow back pain (LBP) is a debilitating condition that affects every population worldwide [1]. It is estimated that 80% of the general population in the United States will develop LBP at one point of time, and similar rates have been noted in other populations as well [1]. Following the common cold, LBP is the second most prevalent condition motivating patients to seek medical consultation [1]. Such pain may lead to diminished daily function and quality of life, loss of wages, psychological distress, and potential brain tissue deterioration [2–4]. Full-Text PDF Samartzis et al. respondThe Spine JournalVol. 13Issue 3PreviewWe thank Mellor and Breen [1] for their letter, entitled “Ionizing radiation exposure and the development of intervertebral disc degeneration—no case to answer.” We are happy to see our “perspective” article raising discussion and consideration of how low-to-moderate levels of ionizing radiation exposure can affect the spine, in particular, the intervertebral disc [2]. Although we appreciate the authors' insights and concerns, we respectfully disagree with them on several fronts. Full-Text PDF" @default.
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• W2094749853 date "2013-03-01" @default.
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• W2094749853 title "Ionizing radiation exposure and the development of intervertebral disc degeneration—no case to answer" @default.
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• W2094749853 doi "https://doi.org/10.1016/j.spinee.2012.07.039" @default.
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