FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2094769730> ?p ?o ?g. }

• W2094769730 endingPage "384" @default.
• W2094769730 startingPage "379" @default.
• W2094769730 abstract "Purpose of review There is no consensus on the ideal treatment of patients with a benign nontoxic multinodular goiter. In some European countries, 131I therapy has replaced surgery as the treatment of choice in these patients. Recombinant human thyrotropin (rhTSH) is a very potent stimulator of the thyroid gland and this review focuses on rhTSH-stimulated 131I therapy. Recent findings The concept of rhTSH-stimulated 131I therapy has been tested in several trials during the last 8 years. With this treatment, the goiter reduction is improved by 35–55%, compared with 131I therapy without rhTSH stimulation. RhTSH prestimulation is particularly beneficial in patients with very large goiters and in those with a low baseline thyroid 131I uptake. In addition, this therapy facilitates tracheal decompression leading to improved respiratory function. RhTSH-stimulated 131I therapy results in a higher rate of permanent hypothyroidism, whereas other side-effects are very modest when using a rhTSH dose of 0.1 mg or below. Summary RhTSH-stimulated radioiodine therapy of benign nontoxic multinodular goiter is still an off-label use but several trials have shown that this treatment is significantly more effective than 131I therapy without rhTSH. However, no trial has yet compared 131I therapy and surgery head-to-head, and future trials should include evaluation of quality of life and cost." @default.
• W2094769730 created "2016-06-24" @default.
• W2094769730 creator A5039528393 @default.
• W2094769730 creator A5072144010 @default.
• W2094769730 date "2009-10-01" @default.
• W2094769730 modified "2023-10-18" @default.
• W2094769730 title "A 30-year perspective on radioiodine therapy of benign nontoxic multinodular goiter*" @default.
• W2094769730 cites W1964535246 @default.
• W2094769730 cites W1967914320 @default.
• W2094769730 cites W1972306445 @default.
• W2094769730 cites W1974279346 @default.
• W2094769730 cites W1976605905 @default.
• W2094769730 cites W1982054347 @default.
• W2094769730 cites W1992256686 @default.
• W2094769730 cites W1997556550 @default.
• W2094769730 cites W2000784270 @default.
• W2094769730 cites W2007174159 @default.
• W2094769730 cites W2014163943 @default.
• W2094769730 cites W2018454192 @default.
• W2094769730 cites W2024947144 @default.
• W2094769730 cites W2030805128 @default.
• W2094769730 cites W2033194982 @default.
• W2094769730 cites W2033676871 @default.
• W2094769730 cites W2034293195 @default.
• W2094769730 cites W2035279372 @default.
• W2094769730 cites W2037925360 @default.
• W2094769730 cites W2053669525 @default.
• W2094769730 cites W2069696291 @default.
• W2094769730 cites W2080272626 @default.
• W2094769730 cites W2080530458 @default.
• W2094769730 cites W2091539228 @default.
• W2094769730 cites W2092184752 @default.
• W2094769730 cites W2093457660 @default.
• W2094769730 cites W2093832760 @default.
• W2094769730 cites W2100992577 @default.
• W2094769730 cites W2101280599 @default.
• W2094769730 cites W2102109637 @default.
• W2094769730 cites W2103505929 @default.
• W2094769730 cites W2107116656 @default.
• W2094769730 cites W2128131202 @default.
• W2094769730 cites W2133158853 @default.
• W2094769730 cites W2139747656 @default.
• W2094769730 cites W2140485458 @default.
• W2094769730 cites W2145791055 @default.
• W2094769730 cites W2151464162 @default.
• W2094769730 cites W2151609680 @default.
• W2094769730 cites W2154432650 @default.
• W2094769730 cites W2170043543 @default.
• W2094769730 cites W2171587699 @default.
• W2094769730 cites W2406691699 @default.
• W2094769730 doi "https://doi.org/10.1097/med.0b013e32832ff2e1" @default.
• W2094769730 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19623060" @default.
• W2094769730 hasPublicationYear "2009" @default.
• W2094769730 type Work @default.
• W2094769730 sameAs 2094769730 @default.
• W2094769730 citedByCount "31" @default.
• W2094769730 countsByYear W20947697302012 @default.
• W2094769730 countsByYear W20947697302013 @default.
• W2094769730 countsByYear W20947697302014 @default.
• W2094769730 countsByYear W20947697302015 @default.
• W2094769730 countsByYear W20947697302017 @default.
• W2094769730 countsByYear W20947697302018 @default.
• W2094769730 countsByYear W20947697302019 @default.
• W2094769730 countsByYear W20947697302020 @default.
• W2094769730 countsByYear W20947697302021 @default.
• W2094769730 countsByYear W20947697302022 @default.
• W2094769730 countsByYear W20947697302023 @default.
• W2094769730 crossrefType "journal-article" @default.
• W2094769730 hasAuthorship W2094769730A5039528393 @default.
• W2094769730 hasAuthorship W2094769730A5072144010 @default.
• W2094769730 hasConcept C126322002 @default.
• W2094769730 hasConcept C141071460 @default.
• W2094769730 hasConcept C2776254400 @default.
• W2094769730 hasConcept C2777074255 @default.
• W2094769730 hasConcept C2779761222 @default.
• W2094769730 hasConcept C2909991657 @default.
• W2094769730 hasConcept C3018694869 @default.
• W2094769730 hasConcept C509974204 @default.
• W2094769730 hasConcept C526584372 @default.
• W2094769730 hasConcept C71924100 @default.
• W2094769730 hasConceptScore W2094769730C126322002 @default.
• W2094769730 hasConceptScore W2094769730C141071460 @default.
• W2094769730 hasConceptScore W2094769730C2776254400 @default.
• W2094769730 hasConceptScore W2094769730C2777074255 @default.
• W2094769730 hasConceptScore W2094769730C2779761222 @default.
• W2094769730 hasConceptScore W2094769730C2909991657 @default.
• W2094769730 hasConceptScore W2094769730C3018694869 @default.
• W2094769730 hasConceptScore W2094769730C509974204 @default.
• W2094769730 hasConceptScore W2094769730C526584372 @default.
• W2094769730 hasConceptScore W2094769730C71924100 @default.
• W2094769730 hasIssue "5" @default.
• W2094769730 hasLocation W20947697301 @default.
• W2094769730 hasLocation W20947697302 @default.
• W2094769730 hasOpenAccess W2094769730 @default.
• W2094769730 hasPrimaryLocation W20947697301 @default.
• W2094769730 hasRelatedWork W2080313118 @default.
• W2094769730 hasRelatedWork W2351684448 @default.
• W2094769730 hasRelatedWork W2377711863 @default.

• next