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• W2094790784 abstract "Desmosomes are essential adhesion structures in most epithelia that link the intermediate filament network of one cell to its neighbor, thereby forming a strong bond. The molecular components of desmosomes belong to the cadherin superfamily, the plakin family, and the armadillo repeat protein family. The desmosomal cadherins are calcium-dependent transmembrane adhesion molecules and comprise the desmogleins and desmocollins. To date, three human desmoglein isoforms have been characterized, namely desmogleins 1, 2, and 3 that are expressed in a tissue- and differentiation-specific manner. Here we have identified and characterized, at the genetic level, a novel human desmoglein cDNA sharing homology with desmogleins 1, 2, 3 and we name this desmoglein 4. The human desmoglein 4 cDNA (3.6 kb) contains an open reading frame of 3120 bp that encodes a precursor protein of 1040 amino acids. The predicted mature protein comprises 991 amino acids with a molecular weight of 107822 Da at pI 4.38. Human desmoglein 4 shares 41% identity with human desmoglein 1, 37% with human desmoglein 2, and 50% with human desmoglein 3. Analysis of the exon/intron organization of the human desmoglein 4 gene (DSG4) demonstrates that it is composed of 16 exons spanning approximately 37 kb of 18q12 and is situated between DSG1 and DSG3. We have demonstrated using RT-PCR on multiple tissue cDNA samples that desmoglein 4 has very specific tissue expression in salivary gland, testis, prostate, and skin." @default.
• W2094790784 created "2016-06-24" @default.
• W2094790784 creator A5034603883 @default.
• W2094790784 creator A5077531693 @default.
• W2094790784 date "2003-04-01" @default.
• W2094790784 modified "2023-10-18" @default.
• W2094790784 title "Genetic Evidence for a Novel Human Desmosomal Cadherin, Desmoglein 4" @default.
• W2094790784 cites W109700311 @default.
• W2094790784 cites W1484921247 @default.
• W2094790784 cites W1500594923 @default.
• W2094790784 cites W1542487405 @default.
• W2094790784 cites W1819034630 @default.
• W2094790784 cites W1868042911 @default.
• W2094790784 cites W1949189176 @default.
• W2094790784 cites W1960127159 @default.
• W2094790784 cites W1963797029 @default.
• W2094790784 cites W1965985288 @default.
• W2094790784 cites W1966163497 @default.
• W2094790784 cites W1966241991 @default.
• W2094790784 cites W1967542165 @default.
• W2094790784 cites W1972759188 @default.
• W2094790784 cites W1976785613 @default.
• W2094790784 cites W1977552066 @default.
• W2094790784 cites W1979374001 @default.
• W2094790784 cites W1982984392 @default.
• W2094790784 cites W1990304254 @default.
• W2094790784 cites W1990972380 @default.
• W2094790784 cites W1992061843 @default.
• W2094790784 cites W1993631303 @default.
• W2094790784 cites W1994453803 @default.
• W2094790784 cites W1995466449 @default.
• W2094790784 cites W1995875428 @default.
• W2094790784 cites W1997105701 @default.
• W2094790784 cites W1997829811 @default.
• W2094790784 cites W2001928302 @default.
• W2094790784 cites W2007249515 @default.
• W2094790784 cites W2011407608 @default.
• W2094790784 cites W2011498938 @default.
• W2094790784 cites W2020113731 @default.
• W2094790784 cites W2020311023 @default.
• W2094790784 cites W2021559685 @default.
• W2094790784 cites W2028851968 @default.
• W2094790784 cites W2030635244 @default.
• W2094790784 cites W2034938648 @default.
• W2094790784 cites W2035135968 @default.
• W2094790784 cites W2036964986 @default.
• W2094790784 cites W2038331484 @default.
• W2094790784 cites W2038665141 @default.
• W2094790784 cites W2039356805 @default.
• W2094790784 cites W2041691970 @default.
• W2094790784 cites W2042908804 @default.
• W2094790784 cites W2046944232 @default.
• W2094790784 cites W2049510891 @default.
• W2094790784 cites W2052484848 @default.
• W2094790784 cites W2056989689 @default.
• W2094790784 cites W2062510055 @default.
• W2094790784 cites W2063271223 @default.
• W2094790784 cites W2063579519 @default.
• W2094790784 cites W2065528492 @default.
• W2094790784 cites W2068233069 @default.
• W2094790784 cites W2077463637 @default.
• W2094790784 cites W2080986404 @default.
• W2094790784 cites W2086111271 @default.
• W2094790784 cites W2090525833 @default.
• W2094790784 cites W2090667517 @default.
• W2094790784 cites W2094800200 @default.
• W2094790784 cites W2095192967 @default.
• W2094790784 cites W2103292732 @default.
• W2094790784 cites W2104635208 @default.
• W2094790784 cites W2107347233 @default.
• W2094790784 cites W2110429029 @default.
• W2094790784 cites W2113436333 @default.
• W2094790784 cites W2115419170 @default.
• W2094790784 cites W2116239421 @default.
• W2094790784 cites W2127124640 @default.
• W2094790784 cites W2128278177 @default.
• W2094790784 cites W2131186777 @default.
• W2094790784 cites W2133462524 @default.
• W2094790784 cites W2139781265 @default.
• W2094790784 cites W2144891441 @default.
• W2094790784 cites W2148952049 @default.
• W2094790784 cites W2149528796 @default.
• W2094790784 cites W2152786893 @default.
• W2094790784 cites W2159568631 @default.
• W2094790784 cites W2159870760 @default.
• W2094790784 cites W2341466010 @default.
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• W2094790784 doi "https://doi.org/10.1046/j.1523-1747.2003.12113.x" @default.
• W2094790784 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12648213" @default.
• W2094790784 hasPublicationYear "2003" @default.
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