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- W2094844881 abstract "Noise analysis of rabbit bladder revealed two components: Lorentzian noise, arising from interaction of amiloride with the Na+ channel, and flicker noise (l/f, where f is frequency), as in other biological membranes. Hydrostatic pressure, which causes exchange between intracellular vesicular membrane and apical membrane, increases the number but not the single-channel current of the amiloride-sensitive channels. Flicker noise arises from degraded channels that have lost amiloride sensitivity and Na+ to K+ selectivity. The degraded channels were selectively removed by washing the mucosal surface. These results imply channel turnover by intracellular synthesis, transfer from vesicular to apical membrane, degradation, and elimination." @default.
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- W2094844881 date "1983-09-23" @default.
- W2094844881 modified "2023-10-15" @default.
- W2094844881 title "Turnover, Membrane Insertion, and Degradation of Sodium Channels in Rabbit Urinary Bladder" @default.
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- W2094844881 doi "https://doi.org/10.1126/science.6612343" @default.
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