Matches in SemOpenAlex for { <https://semopenalex.org/work/W2094947958> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2094947958 abstract "Our purpose was to compare the actions of atrial natriuretic peptide and brain natriuretic peptide in the human placental vasculature.Isolated placental cotyledons were dually perfused with fetal perfusion pressure used as an index of vascular response. The effect of angiotensin II (10(-10) to 10(-6) mol/L bolus injection) was established in the absence or presence of atrial natriuretic peptide (10(-8) mol/L) or brain natriuretic peptide (10(-8) mol/L final concentration). The role of nitric oxide as a mediator of natriuretic peptide action was investigated by perfusion of n-nitro-L-arginine (10(-3) mol/L), an inhibitor of nitric oxide synthase. Attenuation of the action of atrial natriuretic peptide by placental peptidases was studied by perfusion with the peptidase inhibitor benzamidine (2 x 10(-2) mol/L). Statistical significance was determined by analysis of variance and paired t test.Significant attenuation of vasoconstrictor responses to angiotensin II occurred within both atrial natriuretic peptide and brain natriuretic peptide; however, brain natriuretic peptide was more effective. n-Nitro-L-arginine did not affect the attenuation of angiotensin II-induced vasoconstriction by atrial or brain natriuretic peptides. In the presence of benzamidine atrial natriuretic peptide exerted a significantly greater vasodilator effect.Brain natriuretic peptide is a more potent vasodilator of the placental vasculature than is atrial natriuretic peptide. The low efficacy of atrial natriuretic peptide may be related to placental peptidases. Nitric oxide does not mediate the action of atrial natriuretic peptide or brain natriuretic peptide." @default.
- W2094947958 created "2016-06-24" @default.
- W2094947958 creator A5021927168 @default.
- W2094947958 creator A5032661534 @default.
- W2094947958 creator A5040500290 @default.
- W2094947958 creator A5048209900 @default.
- W2094947958 creator A5061152811 @default.
- W2094947958 date "1995-01-01" @default.
- W2094947958 modified "2023-09-23" @default.
- W2094947958 title "The action of two natriuretic peptides (atrial natriuretic peptide and brain natriuretic peptide) in the human placental vasculature" @default.
- W2094947958 cites W1553668020 @default.
- W2094947958 cites W1605314587 @default.
- W2094947958 cites W1965293430 @default.
- W2094947958 cites W1971613811 @default.
- W2094947958 cites W1973452215 @default.
- W2094947958 cites W1975632761 @default.
- W2094947958 cites W1975728622 @default.
- W2094947958 cites W1979659033 @default.
- W2094947958 cites W1988405258 @default.
- W2094947958 cites W1992905322 @default.
- W2094947958 cites W1995787496 @default.
- W2094947958 cites W2005257617 @default.
- W2094947958 cites W2025297094 @default.
- W2094947958 cites W2049664335 @default.
- W2094947958 cites W2054423282 @default.
- W2094947958 cites W2054649519 @default.
- W2094947958 cites W2080512195 @default.
- W2094947958 cites W2098481962 @default.
- W2094947958 cites W2144133816 @default.
- W2094947958 cites W2471455732 @default.
- W2094947958 doi "https://doi.org/10.1016/0002-9378(95)90086-1" @default.
- W2094947958 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7847563" @default.
- W2094947958 hasPublicationYear "1995" @default.
- W2094947958 type Work @default.
- W2094947958 sameAs 2094947958 @default.
- W2094947958 citedByCount "21" @default.
- W2094947958 countsByYear W20949479582012 @default.
- W2094947958 countsByYear W20949479582013 @default.
- W2094947958 countsByYear W20949479582016 @default.
- W2094947958 countsByYear W20949479582018 @default.
- W2094947958 countsByYear W20949479582019 @default.
- W2094947958 crossrefType "journal-article" @default.
- W2094947958 hasAuthorship W2094947958A5021927168 @default.
- W2094947958 hasAuthorship W2094947958A5032661534 @default.
- W2094947958 hasAuthorship W2094947958A5040500290 @default.
- W2094947958 hasAuthorship W2094947958A5048209900 @default.
- W2094947958 hasAuthorship W2094947958A5061152811 @default.
- W2094947958 hasConcept C120770815 @default.
- W2094947958 hasConcept C126322002 @default.
- W2094947958 hasConcept C134018914 @default.
- W2094947958 hasConcept C198710026 @default.
- W2094947958 hasConcept C2775846464 @default.
- W2094947958 hasConcept C2775915353 @default.
- W2094947958 hasConcept C2778069365 @default.
- W2094947958 hasConcept C2778198053 @default.
- W2094947958 hasConcept C2908929049 @default.
- W2094947958 hasConcept C3156946 @default.
- W2094947958 hasConcept C71924100 @default.
- W2094947958 hasConcept C84393581 @default.
- W2094947958 hasConcept C8741621 @default.
- W2094947958 hasConceptScore W2094947958C120770815 @default.
- W2094947958 hasConceptScore W2094947958C126322002 @default.
- W2094947958 hasConceptScore W2094947958C134018914 @default.
- W2094947958 hasConceptScore W2094947958C198710026 @default.
- W2094947958 hasConceptScore W2094947958C2775846464 @default.
- W2094947958 hasConceptScore W2094947958C2775915353 @default.
- W2094947958 hasConceptScore W2094947958C2778069365 @default.
- W2094947958 hasConceptScore W2094947958C2778198053 @default.
- W2094947958 hasConceptScore W2094947958C2908929049 @default.
- W2094947958 hasConceptScore W2094947958C3156946 @default.
- W2094947958 hasConceptScore W2094947958C71924100 @default.
- W2094947958 hasConceptScore W2094947958C84393581 @default.
- W2094947958 hasConceptScore W2094947958C8741621 @default.
- W2094947958 hasLocation W20949479581 @default.
- W2094947958 hasLocation W20949479582 @default.
- W2094947958 hasOpenAccess W2094947958 @default.
- W2094947958 hasPrimaryLocation W20949479581 @default.
- W2094947958 hasRelatedWork W2002527015 @default.
- W2094947958 hasRelatedWork W2010595494 @default.
- W2094947958 hasRelatedWork W2065903584 @default.
- W2094947958 hasRelatedWork W2074235845 @default.
- W2094947958 hasRelatedWork W2094947958 @default.
- W2094947958 hasRelatedWork W2112312398 @default.
- W2094947958 hasRelatedWork W2132487608 @default.
- W2094947958 hasRelatedWork W2153348972 @default.
- W2094947958 hasRelatedWork W4237738361 @default.
- W2094947958 hasRelatedWork W4245590509 @default.
- W2094947958 isParatext "false" @default.
- W2094947958 isRetracted "false" @default.
- W2094947958 magId "2094947958" @default.
- W2094947958 workType "article" @default.