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- W2094972261 abstract "In this study, we synthesized some natural and semisynthetic prenyloxyphenylpropanoids (e.g., coumarins and cinnamic acid derivatives) and we assessed their in vitro inhibitory activity against farnesyl transferase (FTase) and geranylgeranyl transferase I (GGTase I). No compound was an effective inhibitor of FTase, while farnesyloxycinnamic acids were shown to selectively inhibit GGTase I with IC50 values ranging from 28 to 39 μM." @default.
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- W2094972261 date "2007-05-01" @default.
- W2094972261 modified "2023-09-26" @default.
- W2094972261 title "Prenyloxyphenylpropanoids as novel lead compounds for the selective inhibition of geranylgeranyl transferase I" @default.
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- W2094972261 doi "https://doi.org/10.1016/j.bmcl.2007.01.097" @default.
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