FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2094974920> ?p ?o ?g. }

• W2094974920 endingPage "135" @default.
• W2094974920 startingPage "111" @default.
• W2094974920 abstract "Bezafibrate is a potent hypolipidemic agent, which causes marked proliferation of peroxisomes in rat liver. At the same dosage, bezafibrate is more effective in male than in female rats. This is probably related to divergent pharmacokinetics, which cause differences in drug level in serum and liver. The volume density of peroxisomes and several of their enzymes such as carnitine acetyl transferase and acyl-COA oxidase increase in a dose-related fashion. The hypolipidemic effect of bezafibrate, however, does not correlate with the used dosage. This implies that peroxisomal proliferation may play only a minor role in the hypolipidemic action of bezafibrate. In animals treated for 26 months with 300, 750, or 1500 ppm bezafibrate, the relative liver weight and serum triglycerides did not differ significantly from controls. Peroxisomal proliferation varied in different cells, being most prominent in single hepatocytes. The liver catalase activity was significantly reduced, but carnitine acetyl transferase was increased. Abnormal peroxisomes and mitochondria with longitudinal cristae were quite frequent. In one focus, catalase activity was severely diminished ahd peroxisomes were markedly reduced. The incidence of liver tumors was the same (1-3%) in treated animals as in controls." @default.
• W2094974920 created "2016-06-24" @default.
• W2094974920 creator A5015900652 @default.
• W2094974920 creator A5024073427 @default.
• W2094974920 creator A5045681200 @default.
• W2094974920 creator A5052865708 @default.
• W2094974920 creator A5067771186 @default.
• W2094974920 creator A5078076917 @default.
• W2094974920 creator A5091393293 @default.
• W2094974920 date "1982-05-01" @default.
• W2094974920 modified "2023-09-23" @default.
• W2094974920 title "THE SHORT- AND LONG-TERM EFFECTS OF BEZAFIBRATE IN THE RAT" @default.
• W2094974920 cites W1498697464 @default.
• W2094974920 cites W1573886742 @default.
• W2094974920 cites W1775749144 @default.
• W2094974920 cites W1968542784 @default.
• W2094974920 cites W1972374575 @default.
• W2094974920 cites W1973811477 @default.
• W2094974920 cites W1976976178 @default.
• W2094974920 cites W1980526207 @default.
• W2094974920 cites W1998085419 @default.
• W2094974920 cites W2005411425 @default.
• W2094974920 cites W2008202623 @default.
• W2094974920 cites W2015124930 @default.
• W2094974920 cites W2037412892 @default.
• W2094974920 cites W2058967307 @default.
• W2094974920 cites W2067421512 @default.
• W2094974920 cites W2080632715 @default.
• W2094974920 cites W2147956298 @default.
• W2094974920 cites W2148960873 @default.
• W2094974920 cites W2307633579 @default.
• W2094974920 cites W2471596157 @default.
• W2094974920 cites W2615845755 @default.
• W2094974920 cites W46974184 @default.
• W2094974920 cites W610828965 @default.
• W2094974920 cites W88113176 @default.
• W2094974920 doi "https://doi.org/10.1111/j.1749-6632.1982.tb21410.x" @default.
• W2094974920 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6953842" @default.
• W2094974920 hasPublicationYear "1982" @default.
• W2094974920 type Work @default.
• W2094974920 sameAs 2094974920 @default.
• W2094974920 citedByCount "124" @default.
• W2094974920 countsByYear W20949749202012 @default.
• W2094974920 countsByYear W20949749202013 @default.
• W2094974920 countsByYear W20949749202014 @default.
• W2094974920 countsByYear W20949749202015 @default.
• W2094974920 countsByYear W20949749202016 @default.
• W2094974920 countsByYear W20949749202017 @default.
• W2094974920 countsByYear W20949749202020 @default.
• W2094974920 countsByYear W20949749202021 @default.
• W2094974920 crossrefType "journal-article" @default.
• W2094974920 hasAuthorship W2094974920A5015900652 @default.
• W2094974920 hasAuthorship W2094974920A5024073427 @default.
• W2094974920 hasAuthorship W2094974920A5045681200 @default.
• W2094974920 hasAuthorship W2094974920A5052865708 @default.
• W2094974920 hasAuthorship W2094974920A5067771186 @default.
• W2094974920 hasAuthorship W2094974920A5078076917 @default.
• W2094974920 hasAuthorship W2094974920A5091393293 @default.
• W2094974920 hasConcept C126322002 @default.
• W2094974920 hasConcept C127078168 @default.
• W2094974920 hasConcept C134018914 @default.
• W2094974920 hasConcept C170493617 @default.
• W2094974920 hasConcept C181199279 @default.
• W2094974920 hasConcept C185592680 @default.
• W2094974920 hasConcept C2776151105 @default.
• W2094974920 hasConcept C2776362216 @default.
• W2094974920 hasConcept C2778435403 @default.
• W2094974920 hasConcept C2778979269 @default.
• W2094974920 hasConcept C2779496979 @default.
• W2094974920 hasConcept C38485361 @default.
• W2094974920 hasConcept C55493867 @default.
• W2094974920 hasConcept C71924100 @default.
• W2094974920 hasConcept C86803240 @default.
• W2094974920 hasConceptScore W2094974920C126322002 @default.
• W2094974920 hasConceptScore W2094974920C127078168 @default.
• W2094974920 hasConceptScore W2094974920C134018914 @default.
• W2094974920 hasConceptScore W2094974920C170493617 @default.
• W2094974920 hasConceptScore W2094974920C181199279 @default.
• W2094974920 hasConceptScore W2094974920C185592680 @default.
• W2094974920 hasConceptScore W2094974920C2776151105 @default.
• W2094974920 hasConceptScore W2094974920C2776362216 @default.
• W2094974920 hasConceptScore W2094974920C2778435403 @default.
• W2094974920 hasConceptScore W2094974920C2778979269 @default.
• W2094974920 hasConceptScore W2094974920C2779496979 @default.
• W2094974920 hasConceptScore W2094974920C38485361 @default.
• W2094974920 hasConceptScore W2094974920C55493867 @default.
• W2094974920 hasConceptScore W2094974920C71924100 @default.
• W2094974920 hasConceptScore W2094974920C86803240 @default.
• W2094974920 hasIssue "1" @default.
• W2094974920 hasLocation W20949749201 @default.
• W2094974920 hasLocation W20949749202 @default.
• W2094974920 hasOpenAccess W2094974920 @default.
• W2094974920 hasPrimaryLocation W20949749201 @default.
• W2094974920 hasRelatedWork W152379766 @default.
• W2094974920 hasRelatedWork W1963962065 @default.
• W2094974920 hasRelatedWork W1989017494 @default.
• W2094974920 hasRelatedWork W1999190293 @default.
• W2094974920 hasRelatedWork W2010707937 @default.

• next