FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2095006629> ?p ?o ?g. }

• W2095006629 endingPage "1068" @default.
• W2095006629 startingPage "1064" @default.
• W2095006629 abstract "Specific recognition of cell-targeting systems as host-carriers modified with receptor targeting groups, is a major ambition in the application of supramolecular science to medicine and life science. Genistein (Gen), an isoflavone belonging to the class of phytoestrogens, is of great interest because it has been considered as potential remedy for many kinds of disease. In this work, genistein in aqueous medium and in the presence of an host nanocarrier as amphiphilic cyclodextrin (CyD) modified in the upper rim with oligoethylene hydroxyl groups [(2-oligo(ethyleneoxide)-6-hexylthio)-beta-CyD, SC6OH] at 1:1 molar ratio, has been firstly investigated by UV-vis measurements coupled with circular dichroism data, in order to characterize the drug/macrocycle binding affinity through the formation of the complex. Furthermore, FTIR-ATR technique has been used to detect the complex formation in solid phase and to characterize the functional groups responsible of the solid Gen/SC6OH complex stability. The infrared absorbance spectra of the complex, collected in a wide range of wavenumber and around the physiological temperature, have been analysed and compared with the spectra of the pure compounds and their physical mixture. By monitoring the most significant changes in the shape and position of the absorbance bands of the Gen functional groups, we showed that the formation and/or modification of polar bonds play the main role in the interaction of the drug with the amphiphilic CyD. From the results, Gen is shown to be entangled in SC6OH nanoaggregates, establishing hydrogen bonding with the hydrophilic PEG chains." @default.
• W2095006629 created "2016-06-24" @default.
• W2095006629 creator A5001869354 @default.
• W2095006629 creator A5002209094 @default.
• W2095006629 creator A5007541366 @default.
• W2095006629 creator A5009276531 @default.
• W2095006629 creator A5025730160 @default.
• W2095006629 creator A5029897236 @default.
• W2095006629 creator A5035939668 @default.
• W2095006629 creator A5070320534 @default.
• W2095006629 date "2010-04-01" @default.
• W2095006629 modified "2023-10-18" @default.
• W2095006629 title "Physico-chemical characterization of an amphiphilic cyclodextrin/genistein complex" @default.
• W2095006629 cites W1972224748 @default.
• W2095006629 cites W1986186085 @default.
• W2095006629 cites W2004047460 @default.
• W2095006629 cites W2010127522 @default.
• W2095006629 cites W2014646828 @default.
• W2095006629 cites W2039092501 @default.
• W2095006629 cites W2045622793 @default.
• W2095006629 cites W2049950647 @default.
• W2095006629 cites W2061980821 @default.
• W2095006629 cites W2062248358 @default.
• W2095006629 cites W2068626952 @default.
• W2095006629 cites W2077076372 @default.
• W2095006629 cites W2079594934 @default.
• W2095006629 cites W2094163672 @default.
• W2095006629 cites W2105722555 @default.
• W2095006629 cites W2125241752 @default.
• W2095006629 cites W2147301416 @default.
• W2095006629 cites W2162198641 @default.
• W2095006629 cites W2169723658 @default.
• W2095006629 cites W2197842267 @default.
• W2095006629 cites W2951483764 @default.
• W2095006629 cites W4232697053 @default.
• W2095006629 doi "https://doi.org/10.1016/j.jpba.2009.11.025" @default.
• W2095006629 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20036091" @default.
• W2095006629 hasPublicationYear "2010" @default.
• W2095006629 type Work @default.
• W2095006629 sameAs 2095006629 @default.
• W2095006629 citedByCount "44" @default.
• W2095006629 countsByYear W20950066292012 @default.
• W2095006629 countsByYear W20950066292013 @default.
• W2095006629 countsByYear W20950066292014 @default.
• W2095006629 countsByYear W20950066292015 @default.
• W2095006629 countsByYear W20950066292016 @default.
• W2095006629 countsByYear W20950066292017 @default.
• W2095006629 countsByYear W20950066292019 @default.
• W2095006629 countsByYear W20950066292020 @default.
• W2095006629 countsByYear W20950066292021 @default.
• W2095006629 countsByYear W20950066292022 @default.
• W2095006629 countsByYear W20950066292023 @default.
• W2095006629 crossrefType "journal-article" @default.
• W2095006629 hasAuthorship W2095006629A5001869354 @default.
• W2095006629 hasAuthorship W2095006629A5002209094 @default.
• W2095006629 hasAuthorship W2095006629A5007541366 @default.
• W2095006629 hasAuthorship W2095006629A5009276531 @default.
• W2095006629 hasAuthorship W2095006629A5025730160 @default.
• W2095006629 hasAuthorship W2095006629A5029897236 @default.
• W2095006629 hasAuthorship W2095006629A5035939668 @default.
• W2095006629 hasAuthorship W2095006629A5070320534 @default.
• W2095006629 hasConcept C112887158 @default.
• W2095006629 hasConcept C126322002 @default.
• W2095006629 hasConcept C133571119 @default.
• W2095006629 hasConcept C15920480 @default.
• W2095006629 hasConcept C178790620 @default.
• W2095006629 hasConcept C184651966 @default.
• W2095006629 hasConcept C185592680 @default.
• W2095006629 hasConcept C21951064 @default.
• W2095006629 hasConcept C2778298627 @default.
• W2095006629 hasConcept C2779433975 @default.
• W2095006629 hasConcept C32909587 @default.
• W2095006629 hasConcept C43617362 @default.
• W2095006629 hasConcept C521977710 @default.
• W2095006629 hasConcept C67407626 @default.
• W2095006629 hasConcept C71240020 @default.
• W2095006629 hasConcept C71924100 @default.
• W2095006629 hasConcept C90260826 @default.
• W2095006629 hasConcept C93275456 @default.
• W2095006629 hasConcept C98015330 @default.
• W2095006629 hasConceptScore W2095006629C112887158 @default.
• W2095006629 hasConceptScore W2095006629C126322002 @default.
• W2095006629 hasConceptScore W2095006629C133571119 @default.
• W2095006629 hasConceptScore W2095006629C15920480 @default.
• W2095006629 hasConceptScore W2095006629C178790620 @default.
• W2095006629 hasConceptScore W2095006629C184651966 @default.
• W2095006629 hasConceptScore W2095006629C185592680 @default.
• W2095006629 hasConceptScore W2095006629C21951064 @default.
• W2095006629 hasConceptScore W2095006629C2778298627 @default.
• W2095006629 hasConceptScore W2095006629C2779433975 @default.
• W2095006629 hasConceptScore W2095006629C32909587 @default.
• W2095006629 hasConceptScore W2095006629C43617362 @default.
• W2095006629 hasConceptScore W2095006629C521977710 @default.
• W2095006629 hasConceptScore W2095006629C67407626 @default.
• W2095006629 hasConceptScore W2095006629C71240020 @default.
• W2095006629 hasConceptScore W2095006629C71924100 @default.
• W2095006629 hasConceptScore W2095006629C90260826 @default.
• W2095006629 hasConceptScore W2095006629C93275456 @default.

• next