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- W2095082528 abstract "Positive immunoreactions with α-subunit antibodies were present in 43% of biopsy samples obtained from 147 subsequently operated pituitary adenomas representing all major endocrine types (57 endocrine inactive adenomas, 43 prolactinomas, 30 adenomas causing acromegaly, and 17 adenomas causing Cushing's disease or Nelson's syndrome). Marked variations of the incidence, however, were found among the individual endocrine groups. Positive reactions were present in 63% of endocrine inactive adenomas, 57% of adenomas causing acromegaly, 35% of ACTH-secreting adenomas, and 9% of prolactinomas. A positive α-subunit reaction was accompanied in a minority of cases only with positive glycoprotein hormone-β-subunit reactions. There were 21 pure α-subunit adenomas in the group of endocrine inactive adenomas." @default.
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- W2095082528 date "1988-09-01" @default.
- W2095082528 modified "2023-10-07" @default.
- W2095082528 title "Production of the α-subunit of glycoprotein hormones by pituitary adenomas" @default.
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- W2095082528 doi "https://doi.org/10.1016/s0344-0338(88)80022-0" @default.
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