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• W2095110215 abstract "The swelling behaviour of the general matrix of both normal and abnormally softened articular cartilage was investigated in the context of its relationship to the underlying subchondral bone, the articular surface, and with respect to the primary structural directions represented in its strongly anisotropic collagenous architecture. Swelling behaviours were compared by subjecting tissue specimens under different modes of constraint to a high swelling bathing solution of distilled water and comparing structural changes imaged at the macroscopic, microscopic and ultrastructural levels of resolution. Near zero swelling was observed in the isolated normal general matrix with minimal structural change. By contrast the similarly isolated softened general matrix exhibited large-scale swelling in both the transverse and radial directions. This difference in dimensional stability was attributed to fundamentally different levels of fibril interconnectivity between the 2 matrices. A model of structural transformation is proposed to accommodate fibrillar rearrangements associated with the large-scale swelling in the radial and transverse directions in the softened general matrix." @default.
• W2095110215 created "2016-06-24" @default.
• W2095110215 creator A5003159532 @default.
• W2095110215 creator A5033350189 @default.
• W2095110215 date "1999-04-01" @default.
• W2095110215 modified "2023-09-27" @default.
• W2095110215 title "Concerning the ultrastructural origin of large-scale swelling in articular cartilage" @default.
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• W2095110215 doi "https://doi.org/10.1046/j.1469-7580.1999.19430445.x" @default.
• W2095110215 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1467943" @default.
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