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- W2095120114 endingPage "R166" @default.
- W2095120114 startingPage "R151" @default.
- W2095120114 abstract "Neuroendocrine tumors from gastro-pancreatic origin (GEP-NET) can be responsible for liver metastases. Such metastases can be the dominant part of the disease as well due to the tumor burden itself or the symptoms related to such liver metastases. Intra-arterial therapies are commonly used in liver only or liver-dominant disease and encompass trans-arterial chemoembolization (TACE), trans-arterial embolization (TAE), and radioembolization (RE). TACE performed with drug emulsified in Lipiodol has been used for the past 20 years with reported overall survival in the range of 3–4 years, with objective response up to 75%. Response to TACE is higher when treatment is used as a first-line therapy and degree of liver involvement is lower. Benefit of TACE over TAE is unproven in randomized study, but reported in retrospective studies namely in pancreatic NETs. RE provides early interesting results that need to be further evaluated in terms of benefit and toxicity. Radiofrequency ablation allows control of small size and numbered liver metastases, with low invasiveness. Ideal metastases to target are one metastasis <5 cm, or three metastases <3 cm, or a sum of diameter of all metastases below 8 cm. Ablation therapies can be applied in the lung or in the bones when needed, and more invasive surgery should be probably saved for large-size metastases. Even if the indication of image-guided therapy in the treatment of GEP-NET liver metastases needs to be refined, such therapies allow for manageable invasive set of treatments able to address oligometastatic patients in liver, lung, and bones. These treatments applied locally will save the benefit and the toxicity of systemic therapy for more advanced stage of the disease." @default.
- W2095120114 created "2016-06-24" @default.
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- W2095120114 date "2015-04-01" @default.
- W2095120114 modified "2023-10-16" @default.
- W2095120114 title "GEP-NETS UPDATE: Interventional radiology: role in the treatment of liver metastases from GEP-NETs" @default.
- W2095120114 cites W1482296895 @default.
- W2095120114 cites W1532334298 @default.
- W2095120114 cites W1560654516 @default.
- W2095120114 cites W1597026887 @default.
- W2095120114 cites W1965875277 @default.
- W2095120114 cites W1966696261 @default.
- W2095120114 cites W1971397093 @default.
- W2095120114 cites W1971687813 @default.
- W2095120114 cites W1971826787 @default.
- W2095120114 cites W1971840755 @default.
- W2095120114 cites W1972649112 @default.
- W2095120114 cites W1975289587 @default.
- W2095120114 cites W1975753516 @default.
- W2095120114 cites W1977437175 @default.
- W2095120114 cites W1981671364 @default.
- W2095120114 cites W1982036382 @default.
- W2095120114 cites W1982883211 @default.
- W2095120114 cites W1985104505 @default.
- W2095120114 cites W1985844593 @default.
- W2095120114 cites W1987643142 @default.
- W2095120114 cites W1991357429 @default.
- W2095120114 cites W1991443468 @default.
- W2095120114 cites W1992145366 @default.
- W2095120114 cites W1999553451 @default.
- W2095120114 cites W2000600513 @default.
- W2095120114 cites W2001263019 @default.
- W2095120114 cites W2003860294 @default.
- W2095120114 cites W2004535742 @default.
- W2095120114 cites W2004673269 @default.
- W2095120114 cites W2005499885 @default.
- W2095120114 cites W2005735759 @default.
- W2095120114 cites W2006145913 @default.
- W2095120114 cites W2006821285 @default.
- W2095120114 cites W2010390727 @default.
- W2095120114 cites W2011124928 @default.
- W2095120114 cites W2012694635 @default.
- W2095120114 cites W2014356332 @default.
- W2095120114 cites W2015149820 @default.
- W2095120114 cites W2020267062 @default.
- W2095120114 cites W2023215996 @default.
- W2095120114 cites W2030532139 @default.
- W2095120114 cites W2035214608 @default.
- W2095120114 cites W2036782461 @default.
- W2095120114 cites W2036806360 @default.
- W2095120114 cites W2039240838 @default.
- W2095120114 cites W2039974269 @default.
- W2095120114 cites W2041976618 @default.
- W2095120114 cites W2042124865 @default.
- W2095120114 cites W2045789731 @default.
- W2095120114 cites W2046240033 @default.
- W2095120114 cites W2047757951 @default.
- W2095120114 cites W2052664954 @default.
- W2095120114 cites W2058282345 @default.
- W2095120114 cites W2060777568 @default.
- W2095120114 cites W2062785452 @default.
- W2095120114 cites W2063229296 @default.
- W2095120114 cites W2063661839 @default.
- W2095120114 cites W2065475260 @default.
- W2095120114 cites W2069999129 @default.
- W2095120114 cites W2073592782 @default.
- W2095120114 cites W2077896839 @default.
- W2095120114 cites W2079586464 @default.
- W2095120114 cites W2080222082 @default.
- W2095120114 cites W2086241921 @default.
- W2095120114 cites W2086648036 @default.
- W2095120114 cites W2087656963 @default.
- W2095120114 cites W2088591216 @default.
- W2095120114 cites W2092330827 @default.
- W2095120114 cites W2097508883 @default.
- W2095120114 cites W2103352649 @default.
- W2095120114 cites W2107457664 @default.
- W2095120114 cites W2111050454 @default.
- W2095120114 cites W2115686439 @default.
- W2095120114 cites W2116960604 @default.
- W2095120114 cites W2117283868 @default.
- W2095120114 cites W2136586973 @default.
- W2095120114 cites W2137142564 @default.
- W2095120114 cites W2142317226 @default.
- W2095120114 cites W2142996181 @default.
- W2095120114 cites W2148933046 @default.
- W2095120114 cites W2149214723 @default.
- W2095120114 cites W2154767178 @default.
- W2095120114 cites W2156320099 @default.